4G4I
Crystal structure of glucuronoyl esterase S213A mutant from Sporotrichum thermophile determined at 1.9 A resolution
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 501 |
| Chain | Residue |
| A | LYS56 |
| A | ASP87 |
| A | GOL510 |
| A | HOH881 |
| A | HOH969 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 502 |
| Chain | Residue |
| A | ARG101 |
| A | SER110 |
| A | HOH882 |
| A | GLU90 |
| A | ALA91 |
| A | SER92 |
| A | THR99 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 503 |
| Chain | Residue |
| A | LYS107 |
| A | ASP167 |
| A | LEU168 |
| A | GLY170 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 504 |
| Chain | Residue |
| A | LYS328 |
| A | ALA329 |
| A | ALA393 |
| A | PRO394 |
| A | THR395 |
| A | HOH799 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 505 |
| Chain | Residue |
| A | CYS31 |
| A | VAL33 |
| A | ALA68 |
| A | PRO277 |
| A | HOH708 |
| A | HOH734 |
| A | HOH971 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO A 506 |
| Chain | Residue |
| A | ARG214 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 507 |
| Chain | Residue |
| A | LYS44 |
| A | GLU385 |
| A | TRP386 |
| A | HOH972 |
| A | HOH1032 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 508 |
| Chain | Residue |
| A | LYS217 |
| A | GLN259 |
| A | GLU267 |
| A | TRP310 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 509 |
| Chain | Residue |
| A | SER32 |
| A | THR51 |
| A | SER53 |
| A | GLU55 |
| A | GLU193 |
| A | HOH625 |
| A | HOH704 |
| site_id | BC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A 510 |
| Chain | Residue |
| A | ASP47 |
| A | PHE49 |
| A | THR50 |
| A | LYS56 |
| A | TRP389 |
| A | GLY392 |
| A | EDO501 |
| A | HOH626 |
| A | HOH649 |
| A | HOH883 |
| A | HOH969 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 511 |
| Chain | Residue |
| A | ARG116 |
| A | ILE137 |
| A | PRO138 |
| A | VAL141 |
| A | ALA142 |
| A | THR143 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Motif: {"description":"GXSYXG catalytic site motif","evidences":[{"source":"PubMed","id":"20473662","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"20473662","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23275164","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"23275164","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23275164","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
