Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| A | 0034440 | biological_process | lipid oxidation |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE2 A 701 |
| Chain | Residue |
| A | HIS377 |
| A | HIS382 |
| A | HIS555 |
| A | ASN559 |
| A | ILE685 |
| A | HOH801 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ZPE A 702 |
| Chain | Residue |
| A | ASP190 |
| A | LEU193 |
| A | GLU373 |
| A | HIS382 |
| A | PHE415 |
| A | ILE416 |
| A | ALA420 |
| A | ARG422 |
| A | ILE423 |
| A | LEU424 |
| A | TYR609 |
| A | ILE685 |
| A | HOH846 |
| A | HOH852 |
| A | HOH853 |
| A | HOH1195 |
| A | HOH1244 |
| A | LEU182 |
| A | VAL185 |
| A | GLY186 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 703 |
| Chain | Residue |
| A | GLU99 |
| A | CYS389 |
| A | GLN393 |
| A | ALA407 |
| A | PHE410 |
| A | GLU411 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 704 |
| Chain | Residue |
| A | ARG248 |
| A | ASP287 |
| A | HOH836 |
| A | HOH1121 |
| A | HOH1359 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 705 |
| Chain | Residue |
| A | LYS527 |
| A | ARG619 |
| A | ARG678 |
| A | HOH1382 |
| A | HOH1404 |
| A | HOH1451 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 706 |
| Chain | Residue |
| A | ARG229 |
| A | ASP231 |
| A | ARG345 |
| A | PRO346 |
| A | TYR354 |
| A | TRP357 |
| A | GLN358 |
| A | LYS361 |
| A | HOH954 |
| A | HOH1426 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 707 |
| Chain | Residue |
| A | ALA658 |
| A | THR659 |
| A | THR662 |
| A | HOH1352 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 708 |
| Chain | Residue |
| A | GLN493 |
| A | ALA496 |
| A | ASP497 |
| A | ALA500 |
| A | HOH1027 |
| A | HOH1065 |
| A | HOH1145 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 709 |
| Chain | Residue |
| A | TYR456 |
| A | GLU542 |
| A | HOH1044 |
| A | HOH1395 |
| A | HOH1425 |
| A | HOH1441 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 710 |
| Chain | Residue |
| A | ASP582 |
| A | SER583 |
| A | HOH1293 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 711 |
| Chain | Residue |
| A | GLY530 |
| A | PHE531 |
| A | ARG532 |
| A | ALA658 |
| A | ARG661 |
| A | THR662 |
| A | GLN665 |
| A | HOH873 |
| A | HOH1043 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 712 |
| Chain | Residue |
| A | ARG220 |
| A | PRO222 |
| A | PRO563 |
| A | HIS610 |
| A | HOH911 |
| A | HOH1218 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 713 |
| Chain | Residue |
| A | GLU262 |
| A | ARG266 |
| A | VAL501 |
| A | TYR502 |
| A | ARG638 |
| A | HOH938 |
| A | HOH1150 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 714 |
| Chain | Residue |
| A | GLY448 |
| A | LEU451 |
| A | HOH1423 |
| A | LYS87 |
| A | GLY88 |
| A | ALA444 |
| A | GLY447 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 715 |
| Chain | Residue |
| A | ASP506 |
| A | THR535 |
| A | GLY536 |
| A | GLN539 |
| A | HOH1449 |
Functional Information from PROSITE/UniProt
| site_id | PS00081 |
| Number of Residues | 11 |
| Details | LIPOXYGENASE_2 Lipoxygenases iron-binding region signature 2. SHPLhVLLaPH |
| Chain | Residue | Details |
| A | SER399-HIS409 | |
| site_id | PS00711 |
| Number of Residues | 15 |
| Details | LIPOXYGENASE_1 Lipoxygenases iron-binding region signature 1. HEmfvHlAQTHLVsE |
| Chain | Residue | Details |
| A | HIS372-GLU386 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS377 | |
| A | HIS382 | |
| A | HIS555 | |
| A | ASN559 | |
| A | ILE685 | |
