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4G20

Structural basis for the accommodation of bis- and tris-aromatic derivatives in Vitamin D Nuclear Receptor

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues16
DetailsBINDING SITE FOR RESIDUE 484 A 501
ChainResidue
ATYR175
ASER306
AVAL328
AHIS333
ALEU338
AHIS423
ATYR427
ALEU440
AALA259
ALEU261
AVAL262
ASER265
AILE296
AMET300
AARG302
ASER303

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
BSER699
ALEU255
AILE299
AHIS333
AHIS423

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PDB entries from 2024-04-24

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