4G1K
Crystal structure of triosephosphate isomerase from Burkholderia thailandensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004807 | molecular_function | triose-phosphate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019563 | biological_process | glycerol catabolic process |
| A | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| B | 0004807 | molecular_function | triose-phosphate isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006094 | biological_process | gluconeogenesis |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019563 | biological_process | glycerol catabolic process |
| B | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| C | 0004807 | molecular_function | triose-phosphate isomerase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006094 | biological_process | gluconeogenesis |
| C | 0006096 | biological_process | glycolytic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0019563 | biological_process | glycerol catabolic process |
| C | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| D | 0004807 | molecular_function | triose-phosphate isomerase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006094 | biological_process | gluconeogenesis |
| D | 0006096 | biological_process | glycolytic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0019563 | biological_process | glycerol catabolic process |
| D | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 301 |
| Chain | Residue |
| A | PHE223 |
| A | GLN225 |
| A | ILE228 |
| A | HOH543 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 302 |
| Chain | Residue |
| A | GLY124 |
| A | LEU125 |
| A | ARG165 |
| A | HOH485 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 303 |
| Chain | Residue |
| A | GLY21 |
| A | ASN22 |
| A | HOH497 |
| A | HOH530 |
| A | GLY17 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 304 |
| Chain | Residue |
| A | ARG118 |
| A | LEU121 |
| A | ALA122 |
| A | GLU162 |
| A | ARG165 |
| D | ARG165 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 301 |
| Chain | Residue |
| B | PHE223 |
| B | GLN225 |
| B | ILE228 |
| B | HOH513 |
| B | HOH554 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 302 |
| Chain | Residue |
| B | GLY124 |
| B | LEU125 |
| B | ARG165 |
| B | HOH434 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 303 |
| Chain | Residue |
| B | GLY17 |
| B | GLY21 |
| B | ASN22 |
| B | LEU25 |
| B | HOH525 |
| B | HOH526 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 304 |
| Chain | Residue |
| B | ARG8 |
| B | TYR94 |
| B | THR126 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA C 301 |
| Chain | Residue |
| C | PHE223 |
| C | GLN225 |
| C | ILE228 |
| C | HOH462 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 302 |
| Chain | Residue |
| B | GLY124 |
| C | GLY124 |
| C | LEU125 |
| C | THR126 |
| C | ARG165 |
| C | HOH437 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 303 |
| Chain | Residue |
| C | GLY17 |
| C | GLY21 |
| C | ASN22 |
| C | LEU25 |
| C | LEU238 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 304 |
| Chain | Residue |
| C | ARG8 |
| C | SER64 |
| C | THR126 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA D 301 |
| Chain | Residue |
| D | PHE223 |
| D | GLN225 |
| D | ILE228 |
| D | HOH475 |
| D | HOH506 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 302 |
| Chain | Residue |
| D | GLY124 |
| D | LEU125 |
| D | THR126 |
| D | ARG165 |
| D | HOH417 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT D 303 |
| Chain | Residue |
| D | SER213 |
| D | GLY234 |
| D | GLY235 |
| D | HOH407 |
| D | HOH477 |
| D | HOH500 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 304 |
| Chain | Residue |
| D | HIS16 |
| D | GLY21 |
| D | ASN22 |
| D | LEU25 |
| D | LEU238 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 26 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGTGKSATAEqAqqvhaflrgr........LAAK |
| Chain | Residue | Details |
| A | ILE176-LYS201 |
| site_id | PS00171 |
| Number of Residues | 11 |
| Details | TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG |
| Chain | Residue | Details |
| A | ALA169-GLY179 |
