4FYK

Crystal structure of rcl with 5'-phiosphorothioate-adenosine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009159	biological_process	deoxyribonucleoside monophosphate catabolic process
A	0070694	molecular_function	5-hydroxymethyl-dUMP N-hydrolase activity
B	0009159	biological_process	deoxyribonucleoside monophosphate catabolic process
B	0070694	molecular_function	5-hydroxymethyl-dUMP N-hydrolase activity
C	0009159	biological_process	deoxyribonucleoside monophosphate catabolic process
C	0070694	molecular_function	5-hydroxymethyl-dUMP N-hydrolase activity
D	0009159	biological_process	deoxyribonucleoside monophosphate catabolic process
D	0070694	molecular_function	5-hydroxymethyl-dUMP N-hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE SRA A 201

Chain	Residue
A	CYS15
A	GLY89
A	GLU93
A	HOH309
A	HOH315
A	HOH423
A	HOH457
B	SER117
B	ALA118
B	MET119
A	GLY16
A	ILE18
A	ARG19
A	GLY20
A	GLU44
A	ILE65
A	ASN69
A	SER87

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 202

Chain	Residue
A	ARG37
B	SER33
B	ARG36

---

site_id	AC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE SRA B 201

Chain	Residue
A	SER117
A	ALA118
A	MET119
B	CYS15
B	GLY16
B	ILE18
B	ARG19
B	GLY20
B	ILE65
B	ASN69
B	SER87
B	GLY89
B	GLU93
B	HOH302
B	HOH331
B	HOH376
B	HOH439

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 202

Chain	Residue
A	SER33
B	ARG34
B	ARG37

---

site_id	AC5
Number of Residues	19
Details	BINDING SITE FOR RESIDUE SRA C 201

Chain	Residue
C	CYS15
C	GLY16
C	ILE18
C	ARG19
C	GLY20
C	ILE65
C	ASN69
C	SER87
C	GLY89
C	VAL90
C	GLU93
C	HOH303
C	HOH324
C	HOH325
C	HOH395
C	HOH405
D	SER117
D	ALA118
D	MET119

---

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE SRA D 201

Chain	Residue
C	SER117
C	ALA118
C	MET119
D	CYS15
D	GLY16
D	ILE18
D	ARG19
D	GLY20
D	ILE65
D	ASN69
D	SER87
D	GLY89
D	GLU93
D	HOH302
D	HOH319
D	HOH344
D	HOH394

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 202

Chain	Residue
C	SER33
C	ARG36
D	ARG34
D	ARG37

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23385460","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24260472","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25108359","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FYH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P5D","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"23385460","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24260472","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25108359","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FYH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P5D","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O43598","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"22673903","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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