4FXX
Structure of SF1 coiled-coil domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000398 | biological_process | mRNA splicing, via spliceosome |
| A | 0003723 | molecular_function | RNA binding |
| A | 0045131 | molecular_function | pre-mRNA branch point binding |
| B | 0000398 | biological_process | mRNA splicing, via spliceosome |
| B | 0003723 | molecular_function | RNA binding |
| B | 0045131 | molecular_function | pre-mRNA branch point binding |
| C | 0000398 | biological_process | mRNA splicing, via spliceosome |
| C | 0003723 | molecular_function | RNA binding |
| C | 0045131 | molecular_function | pre-mRNA branch point binding |
| D | 0000398 | biological_process | mRNA splicing, via spliceosome |
| D | 0003723 | molecular_function | RNA binding |
| D | 0045131 | molecular_function | pre-mRNA branch point binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD A 201 |
| Chain | Residue |
| A | LEU44 |
| A | THR45 |
| A | ARG46 |
| A | GLU49 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MLI A 202 |
| Chain | Residue |
| B | GLU59 |
| A | THR38 |
| A | ASP60 |
| A | HOH309 |
| A | HOH311 |
| B | GLU49 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD B 201 |
| Chain | Residue |
| A | GLU49 |
| A | GLU59 |
| A | HOH301 |
| B | THR38 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IMD B 202 |
| Chain | Residue |
| B | GLY43 |
| B | THR45 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IMD C 201 |
| Chain | Residue |
| C | LEU44 |
| C | GLU49 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD C 202 |
| Chain | Residue |
| C | HOH311 |
| C | HOH313 |
| D | GLY43 |
| D | THR45 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MLI C 203 |
| Chain | Residue |
| C | LEU56 |
| C | ASP60 |
| C | ARG63 |
| C | HOH310 |
| D | GLU59 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IMD D 201 |
| Chain | Residue |
| C | GLU49 |
| C | GLU59 |
| D | THR38 |
| D | LEU56 |
| D | ASP60 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD D 202 |
| Chain | Residue |
| C | VAL54 |
| D | ARG50 |
| D | GLU115 |
| D | LEU119 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IMD D 203 |
| Chain | Residue |
| C | PHE99 |
| C | ARG102 |
| D | GLN29 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER80 | |
| A | SER82 | |
| B | SER80 | |
| B | SER82 | |
| C | SER80 | |
| C | SER82 | |
| D | SER80 | |
| D | SER82 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | TYR87 | |
| B | TYR87 | |
| C | TYR87 | |
| D | TYR87 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER89 | |
| B | SER89 | |
| C | SER89 | |
| D | SER89 |
