4FWU

Crystal structure of glutaminyl cyclase from drosophila melanogaster in space group I4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008270	molecular_function	zinc ion binding
A	0016603	molecular_function	glutaminyl-peptide cyclotransferase activity
A	0016746	molecular_function	acyltransferase activity
A	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:Q16769

Chain	Residue	Details
A	GLU170
A	ASP218

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:22897232, ECO:0007744|PDB:4F9V

Chain	Residue	Details
A	ARG85
A	GLU91

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:22897232, ECO:0000269|PubMed:23545638, ECO:0007744|PDB:4F9U, ECO:0007744|PDB:4F9V, ECO:0007744|PDB:4FWU

Chain	Residue	Details
A	ASP131
A	GLU171
A	HIS297

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:22897232, ECO:0007744|PDB:4F9U

Chain	Residue	Details
A	GLN151
A	ARG155
A	LEU306

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:22897232, ECO:0000269|PubMed:23545638, ECO:0000312|PDB:4FWU, ECO:0007744|PDB:4F9U, ECO:0007744|PDB:4F9V

Chain	Residue	Details
A	ASN42

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
A	ASN156

---