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4FW8

Crystal structure of FABG4 complexed with Coenzyme NADH

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
A0005576cellular_componentextracellular region
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0009274cellular_componentpeptidoglycan-based cell wall
A0016491molecular_functionoxidoreductase activity
A0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A0030497biological_processfatty acid elongation
A0035336biological_processlong-chain fatty-acyl-CoA metabolic process
A0046459biological_processshort-chain fatty acid metabolic process
A0046677biological_processresponse to antibiotic
B0000166molecular_functionnucleotide binding
B0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
B0005576cellular_componentextracellular region
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0009274cellular_componentpeptidoglycan-based cell wall
B0016491molecular_functionoxidoreductase activity
B0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B0030497biological_processfatty acid elongation
B0035336biological_processlong-chain fatty-acyl-CoA metabolic process
B0046459biological_processshort-chain fatty acid metabolic process
B0046677biological_processresponse to antibiotic
C0000166molecular_functionnucleotide binding
C0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
C0005576cellular_componentextracellular region
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0009274cellular_componentpeptidoglycan-based cell wall
C0016491molecular_functionoxidoreductase activity
C0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C0030497biological_processfatty acid elongation
C0035336biological_processlong-chain fatty-acyl-CoA metabolic process
C0046459biological_processshort-chain fatty acid metabolic process
C0046677biological_processresponse to antibiotic
D0000166molecular_functionnucleotide binding
D0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
D0005576cellular_componentextracellular region
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0009274cellular_componentpeptidoglycan-based cell wall
D0016491molecular_functionoxidoreductase activity
D0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D0030497biological_processfatty acid elongation
D0035336biological_processlong-chain fatty-acyl-CoA metabolic process
D0046459biological_processshort-chain fatty acid metabolic process
D0046677biological_processresponse to antibiotic
Functional Information from PDB Data
site_idAC1
Number of Residues21
DetailsBINDING SITE FOR RESIDUE NAI A 501
ChainResidue
AGLY220
AGLY297
AILE298
ALEU345
ASER346
ATYR360
ALYS364
APRO390
AGLY391
AILE393
ATHR395
AARG223
AHOH608
AHOH667
AILE225
AASP244
ALEU266
AASP267
AVAL268
AASN295
AALA296

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE ZPG A 502
ChainResidue
AASN354
BHOH602

site_idAC3
Number of Residues16
DetailsBINDING SITE FOR RESIDUE NAI B 501
ChainResidue
BALA222
BARG223
BILE225
BASP244
BVAL245
BLEU266
BASP267
BVAL268
BASN295
BGLY297
BTYR360
BLYS364
BPRO390
BILE393
BTHR395
BHOH635

site_idAC4
Number of Residues16
DetailsBINDING SITE FOR RESIDUE NAI C 501
ChainResidue
CGLY220
CARG223
CGLY224
CILE225
CASP244
CASP267
CVAL268
CASN295
CGLY297
CILE298
CSER347
CTYR360
CLYS364
CPRO390
CILE393
CHOH602

site_idAC5
Number of Residues17
DetailsBINDING SITE FOR RESIDUE NAI D 501
ChainResidue
DGLY220
DARG223
DILE225
DASP244
DVAL245
DLEU266
DASP267
DVAL268
DASN295
DGLY297
DLEU345
DSER347
DTYR360
DLYS364
DGLY391
DILE393
DTHR395

Functional Information from PROSITE/UniProt
site_idPS00061
Number of Residues29
DetailsADH_SHORT Short-chain dehydrogenases/reductases family signature. SiagiagnrgQtnYATTKAGMiGITqALA
ChainResidueDetails
ASER347-ALA375

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PDB entries from 2024-08-28

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