Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM A 801 |
| Chain | Residue |
| A | TRP409 |
| A | PHE704 |
| A | TYR706 |
| A | H4B802 |
| A | 2KJ803 |
| A | TFA804 |
| A | HOH904 |
| A | HOH914 |
| A | HOH1017 |
| A | HOH1057 |
| A | CYS415 |
| A | VAL416 |
| A | SER457 |
| A | PHE584 |
| A | SER585 |
| A | TRP587 |
| A | GLU592 |
| A | TRP678 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE H4B A 802 |
| Chain | Residue |
| A | SER334 |
| A | ARG596 |
| A | VAL677 |
| A | TRP678 |
| A | HEM801 |
| A | HOH901 |
| A | HOH914 |
| A | HOH926 |
| A | HOH969 |
| A | HOH1061 |
| B | TRP676 |
| B | PHE691 |
| B | HIS692 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 2KJ A 803 |
| Chain | Residue |
| A | GLN478 |
| A | TYR562 |
| A | PRO565 |
| A | VAL567 |
| A | PHE584 |
| A | GLY586 |
| A | TRP587 |
| A | TYR588 |
| A | GLU592 |
| A | ASP597 |
| A | HEM801 |
| A | HOH924 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE TFA A 804 |
| Chain | Residue |
| A | GLY417 |
| A | ILE419 |
| A | TRP587 |
| A | VAL649 |
| A | ALA654 |
| A | SER657 |
| A | HEM801 |
| A | HOH1000 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 805 |
| Chain | Residue |
| A | CYS326 |
| A | CYS331 |
| B | CYS326 |
| B | CYS331 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM B 801 |
| Chain | Residue |
| B | TRP409 |
| B | CYS415 |
| B | SER457 |
| B | PHE584 |
| B | SER585 |
| B | TRP587 |
| B | GLU592 |
| B | PHE704 |
| B | TYR706 |
| B | H4B802 |
| B | 2KJ803 |
| B | TFA804 |
| B | HOH906 |
| B | HOH935 |
| B | HOH958 |
| B | HOH1039 |
| B | HOH1087 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE H4B B 802 |
| Chain | Residue |
| A | TRP676 |
| A | PHE691 |
| A | HIS692 |
| A | GLN693 |
| A | GLU694 |
| B | SER334 |
| B | ARG596 |
| B | VAL677 |
| B | TRP678 |
| B | HEM801 |
| B | HOH903 |
| B | HOH935 |
| B | HOH965 |
| B | HOH982 |
| B | HOH1065 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 2KJ B 803 |
| Chain | Residue |
| B | GLN478 |
| B | TYR562 |
| B | PRO565 |
| B | VAL567 |
| B | PHE584 |
| B | GLY586 |
| B | TRP587 |
| B | TYR588 |
| B | GLU592 |
| B | ASP597 |
| B | HEM801 |
| B | HOH925 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE TFA B 804 |
| Chain | Residue |
| B | GLY417 |
| B | ILE419 |
| B | GLN420 |
| B | TRP587 |
| B | HEM801 |
| B | HOH1125 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG414-TRP421 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | TRP587 | |
| A | TYR588 | |
| A | GLU592 | |
| A | VAL677 | |
| A | TRP678 | |
| A | PHE691 | |
| A | TYR706 | |
| B | SER334 | |
| B | GLN478 | |
| B | TRP587 | |
| B | TYR588 | |
| B | GLU592 | |
| B | VAL677 | |
| B | TRP678 | |
| B | PHE691 | |
| B | TYR706 | |
| A | SER334 | |
| A | GLN478 | |
| Chain | Residue | Details |
| A | CYS415 | |
| B | CYS415 | |
