Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 8UP A 301 |
| Chain | Residue |
| A | ASN11 |
| A | GLY221 |
| A | CYS222 |
| A | GLY229 |
| A | SIN302 |
| A | SER145 |
| A | ASP192 |
| A | SER193 |
| A | GLN195 |
| A | SER198 |
| A | VAL216 |
| A | SER217 |
| A | TRP218 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SIN A 302 |
| Chain | Residue |
| A | VAL30 |
| A | HIS46 |
| A | GLN195 |
| A | GLY196 |
| A | SER198 |
| A | 8UP301 |
| A | HOH439 |
| A | HOH482 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | LYS180 |
| A | HIS236 |
| A | HOH470 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | TYR126 |
| A | ARG233 |
| A | HIS236 |
| A | HOH597 |
| A | HOH616 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 305 |
| Chain | Residue |
| A | LYS53 |
| A | HIS95 |
| A | THR178 |
| A | LYS180 |
| A | MET181 |
| A | HOH427 |
| A | HOH601 |
| A | HOH653 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 306 |
| Chain | Residue |
| A | LYS75 |
| A | LYS106 |
| A | LYS225 |
| A | HOH559 |
| A | HOH610 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 307 |
| Chain | Residue |
| A | VAL27 |
| A | TYR60 |
| A | ARG63 |
| A | LEU66 |
| A | ASN67 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 308 |
| Chain | Residue |
| A | ARG20 |
| A | HIS22 |
| A | ARG23 |
| A | TYR51 |
| A | HOH523 |
| A | HOH665 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 309 |
| Chain | Residue |
| A | THR28 |
| A | TYR29 |
| A | TYR150 |
| A | HOH441 |
| A | HOH482 |
| A | HOH673 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 310 |
| Chain | Residue |
| A | THR178 |
| A | THR179 |
| A | HOH490 |
| A | HOH513 |
| A | HOH601 |
| A | HOH653 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 311 |
| Chain | Residue |
| A | PRO52 |
| A | LEU81 |
| A | THR91 |
| A | HOH433 |
| A | HOH477 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 312 |
| Chain | Residue |
| A | ARG220 |
| A | HOH456 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. ISATHC |
| Chain | Residue | Details |
| A | ILE42-CYS47 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| A | ASP192-VAL203 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 245 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"9151681","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000026"} |
