Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000077 | biological_process | DNA damage checkpoint signaling |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004674 | molecular_function | protein serine/threonine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE 7HK A 301 |
Chain | Residue |
A | GLN13 |
A | SER147 |
A | ASP148 |
A | HOH516 |
A | HOH539 |
A | LEU15 |
A | TYR20 |
A | VAL23 |
A | LYS38 |
A | TYR86 |
A | CYS87 |
A | GLY90 |
A | LEU137 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 302 |
Chain | Residue |
A | LYS54 |
A | ARG129 |
A | THR153 |
A | ARG162 |
A | HOH462 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A 303 |
Chain | Residue |
A | LYS132 |
A | GLU134 |
A | THR170 |
A | HOH502 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 304 |
Chain | Residue |
A | TRP221 |
A | LYS224 |
A | HIS243 |
A | LEU246 |
A | HOH496 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE IPA A 305 |
Chain | Residue |
A | ILE96 |
A | TYR173 |
A | GLY204 |
A | GLU205 |
A | HOH518 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 24 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAYGEVQlAvnrvteea..........VAVK |
Chain | Residue | Details |
A | LEU15-LYS38 | |
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ItHrDIKpeNLLL |
Chain | Residue | Details |
A | ILE126-LEU138 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton acceptor |
Chain | Residue | Details |
A | ASP130 | |
Chain | Residue | Details |
A | LEU15 | |
A | LYS38 | |
Chain | Residue | Details |
A | SER280 | |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:32357935 |
Chain | Residue | Details |
A | LYS132 | |