Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4FO2

Heat-labile enterotoxin LT-IIb-B5(T13I) mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0033644	cellular_component	host cell membrane
A	0044501	biological_process	perturbation of signal transduction in another organism
A	0090729	molecular_function	toxin activity
B	0005576	cellular_component	extracellular region
B	0033644	cellular_component	host cell membrane
B	0044501	biological_process	perturbation of signal transduction in another organism
B	0090729	molecular_function	toxin activity
C	0005576	cellular_component	extracellular region
C	0033644	cellular_component	host cell membrane
C	0044501	biological_process	perturbation of signal transduction in another organism
C	0090729	molecular_function	toxin activity
D	0005576	cellular_component	extracellular region
D	0033644	cellular_component	host cell membrane
D	0044501	biological_process	perturbation of signal transduction in another organism
D	0090729	molecular_function	toxin activity
E	0005576	cellular_component	extracellular region
E	0033644	cellular_component	host cell membrane
E	0044501	biological_process	perturbation of signal transduction in another organism
E	0090729	molecular_function	toxin activity
F	0005576	cellular_component	extracellular region
F	0033644	cellular_component	host cell membrane
F	0044501	biological_process	perturbation of signal transduction in another organism
F	0090729	molecular_function	toxin activity
G	0005576	cellular_component	extracellular region
G	0033644	cellular_component	host cell membrane
G	0044501	biological_process	perturbation of signal transduction in another organism
G	0090729	molecular_function	toxin activity
H	0005576	cellular_component	extracellular region
H	0033644	cellular_component	host cell membrane
H	0044501	biological_process	perturbation of signal transduction in another organism
H	0090729	molecular_function	toxin activity
I	0005576	cellular_component	extracellular region
I	0033644	cellular_component	host cell membrane
I	0044501	biological_process	perturbation of signal transduction in another organism
I	0090729	molecular_function	toxin activity
J	0005576	cellular_component	extracellular region
J	0033644	cellular_component	host cell membrane
J	0044501	biological_process	perturbation of signal transduction in another organism
J	0090729	molecular_function	toxin activity
K	0005576	cellular_component	extracellular region
K	0033644	cellular_component	host cell membrane
K	0044501	biological_process	perturbation of signal transduction in another organism
K	0090729	molecular_function	toxin activity
L	0005576	cellular_component	extracellular region
L	0033644	cellular_component	host cell membrane
L	0044501	biological_process	perturbation of signal transduction in another organism
L	0090729	molecular_function	toxin activity
M	0005576	cellular_component	extracellular region
M	0033644	cellular_component	host cell membrane
M	0044501	biological_process	perturbation of signal transduction in another organism
M	0090729	molecular_function	toxin activity
N	0005576	cellular_component	extracellular region
N	0033644	cellular_component	host cell membrane
N	0044501	biological_process	perturbation of signal transduction in another organism
N	0090729	molecular_function	toxin activity
O	0005576	cellular_component	extracellular region
O	0033644	cellular_component	host cell membrane
O	0044501	biological_process	perturbation of signal transduction in another organism
O	0090729	molecular_function	toxin activity
P	0005576	cellular_component	extracellular region
P	0033644	cellular_component	host cell membrane
P	0044501	biological_process	perturbation of signal transduction in another organism
P	0090729	molecular_function	toxin activity
Q	0005576	cellular_component	extracellular region
Q	0033644	cellular_component	host cell membrane
Q	0044501	biological_process	perturbation of signal transduction in another organism
Q	0090729	molecular_function	toxin activity
R	0005576	cellular_component	extracellular region
R	0033644	cellular_component	host cell membrane
R	0044501	biological_process	perturbation of signal transduction in another organism
R	0090729	molecular_function	toxin activity
S	0005576	cellular_component	extracellular region
S	0033644	cellular_component	host cell membrane
S	0044501	biological_process	perturbation of signal transduction in another organism
S	0090729	molecular_function	toxin activity
T	0005576	cellular_component	extracellular region
T	0033644	cellular_component	host cell membrane
T	0044501	biological_process	perturbation of signal transduction in another organism
T	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA E 101

Chain	Residue
E	ARG12
E	ALA15
E	HOH216
E	HOH217
J	ASN33

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA F 101

Chain	Residue
F	HOH233
F	HOH234
F	ARG12
F	ALA15
F	HOH214
F	HOH232

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA B 101

Chain	Residue
B	ALA15
B	SER16
B	PRO84
B	HOH201
B	HOH220
B	HOH224
H	ASN33

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA C 101

Chain	Residue
C	ARG12
C	ALA15
C	HOH216
C	HOH228
C	HOH229
M	HOH229

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA L 101

Chain	Residue
L	ARG12
L	ALA15
L	SER16
L	HOH212
L	HOH215
O	ASN33

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA M 101

Chain	Residue
M	ARG12
M	ALA15
M	HOH205
M	HOH209
M	HOH224
M	HOH232

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT N 101

Chain	Residue
M	TYR55
M	VAL59
N	ARG51
N	ALA52
N	ASN58
N	THR61
N	ARG65

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA Q 101

Chain	Residue
Q	ARG12
Q	ALA15
Q	SER16
Q	HOH212
Q	HOH213
T	ASN33

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT Q 102

Chain	Residue
P	TYR55
P	VAL59
Q	ALA52
Q	ASN58
Q	THR61
Q	ARG65

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA R 101

Chain	Residue
R	ARG12
R	ALA15
R	HOH204
R	HOH213
R	HOH217
R	HOH232

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)