4FO0
Human actin-related protein Arp8 in its ATP-bound state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000723 | biological_process | telomere maintenance |
| A | 0003729 | molecular_function | mRNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005694 | cellular_component | chromosome |
| A | 0006275 | biological_process | regulation of DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006282 | biological_process | regulation of DNA repair |
| A | 0006302 | biological_process | double-strand break repair |
| A | 0006310 | biological_process | DNA recombination |
| A | 0006338 | biological_process | chromatin remodeling |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0006974 | biological_process | DNA damage response |
| A | 0010604 | biological_process | positive regulation of macromolecule metabolic process |
| A | 0031011 | cellular_component | Ino80 complex |
| A | 0033044 | biological_process | regulation of chromosome organization |
| A | 0045739 | biological_process | positive regulation of DNA repair |
| A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| A | 0045995 | biological_process | regulation of embryonic development |
| A | 0051052 | biological_process | regulation of DNA metabolic process |
| A | 0051301 | biological_process | cell division |
| A | 0051726 | biological_process | regulation of cell cycle |
| A | 0060382 | biological_process | regulation of DNA strand elongation |
| A | 1904507 | biological_process | positive regulation of telomere maintenance in response to DNA damage |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 701 |
| Chain | Residue |
| A | LYS288 |
| A | ATP702 |
| A | HOH844 |
| A | HOH901 |
| A | HOH905 |
| A | HOH907 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE ATP A 702 |
| Chain | Residue |
| A | THR57 |
| A | ARG59 |
| A | GLY285 |
| A | ASP286 |
| A | GLN287 |
| A | LYS288 |
| A | GLY311 |
| A | GLN344 |
| A | LYS347 |
| A | GLU348 |
| A | GLY539 |
| A | GLY540 |
| A | GLY541 |
| A | MET543 |
| A | PHE544 |
| A | MG701 |
| A | HOH809 |
| A | HOH813 |
| A | HOH814 |
| A | HOH815 |
| A | HOH844 |
| A | HOH845 |
| A | HOH901 |
| A | HOH930 |
| A | GLY54 |
| A | SER55 |
| A | THR56 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 703 |
| Chain | Residue |
| A | GLN105 |
| A | PRO395 |
| A | ALA396 |
| A | PHE398 |
| A | GLY399 |
| A | ILE400 |
| A | MET405 |
| A | ALA508 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 704 |
| Chain | Residue |
| A | GLY153 |
| A | ASN154 |
| A | LYS155 |
| A | TYR173 |
| A | HOH823 |
| A | HOH940 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 705 |
| Chain | Residue |
| A | GLN107 |
| A | LEU110 |
| A | LYS111 |
| A | ASP114 |
| A | ASP149 |
| A | HIS150 |
| A | HOH871 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 706 |
| Chain | Residue |
| A | TYR329 |
| A | GLU331 |
| A | GLN333 |
| A | ASP339 |
| A | HOH939 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 707 |
| Chain | Residue |
| A | PHE350 |
| A | HIS363 |
| A | LYS385 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 708 |
| Chain | Residue |
| A | TRP156 |
| A | THR157 |
| A | ASN158 |
| A | THR159 |
| A | SER160 |
| A | ASN175 |
| A | ASP178 |
| A | HOH919 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 709 |
| Chain | Residue |
| A | PRO176 |
| A | THR335 |
| A | ASN336 |
| A | LYS337 |
| A | MET338 |
| A | HOH842 |
| A | HOH929 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 710 |
| Chain | Residue |
| A | GLN44 |
| A | GLN44 |
| A | SER45 |
| A | ALA593 |
| A | CYS594 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 711 |
| Chain | Residue |
| A | MET579 |
| A | ASP580 |
| A | LYS587 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
