4FNR

Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0004557	molecular_function	alpha-galactosidase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0016052	biological_process	carbohydrate catabolic process
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0033531	biological_process	stachyose metabolic process
A	0034484	biological_process	raffinose catabolic process
A	0051289	biological_process	protein homotetramerization
B	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0004557	molecular_function	alpha-galactosidase activity
B	0005975	biological_process	carbohydrate metabolic process
B	0016052	biological_process	carbohydrate catabolic process
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0033531	biological_process	stachyose metabolic process
B	0034484	biological_process	raffinose catabolic process
B	0051289	biological_process	protein homotetramerization
C	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
C	0004557	molecular_function	alpha-galactosidase activity
C	0005975	biological_process	carbohydrate metabolic process
C	0016052	biological_process	carbohydrate catabolic process
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0033531	biological_process	stachyose metabolic process
C	0034484	biological_process	raffinose catabolic process
C	0051289	biological_process	protein homotetramerization
D	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
D	0004557	molecular_function	alpha-galactosidase activity
D	0005975	biological_process	carbohydrate metabolic process
D	0016052	biological_process	carbohydrate catabolic process
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0033531	biological_process	stachyose metabolic process
D	0034484	biological_process	raffinose catabolic process
D	0051289	biological_process	protein homotetramerization

Functional Information from PROSITE/UniProt

site_id	PS00512
Number of Residues	16
Details	ALPHA_GALACTOSIDASE Alpha-galactosidase signature. GIelVvLDDg.Wfge....RD

Chain	Residue	Details
A	GLY359-ASP374

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:23012371

Chain	Residue	Details
A	ASP478
B	ASP478
C	ASP478
D	ASP478

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000269|PubMed:23012371

Chain	Residue	Details
A	ASP548
B	ASP548
C	ASP548
D	ASP548

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site_id	SWS_FT_FI3
Number of Residues	28
Details	BINDING: BINDING => ECO:0000269|PubMed:23012371, ECO:0007744|PDB:4FNT

Chain	Residue	Details
A	ASP53
B	ASP366
B	ARG443
B	LYS476
B	CYS526
B	ASP548
C	ASP53
C	TRP199
C	ASP366
C	ARG443
C	LYS476
A	TRP199
C	CYS526
C	ASP548
D	ASP53
D	TRP199
D	ASP366
D	ARG443
D	LYS476
D	CYS526
D	ASP548
A	ASP366
A	ARG443
A	LYS476
A	CYS526
A	ASP548
B	ASP53
B	TRP199

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