4FMM
Dimeric Sec14 family homolog 3 from Saccharomyces cerevisiae presents some novel features of structure that lead to a surprising "dimer-monomer" state change induced by substrate binding
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005737 | cellular_component | cytoplasm |
A | 0005783 | cellular_component | endoplasmic reticulum |
A | 0005789 | cellular_component | endoplasmic reticulum membrane |
A | 0005811 | cellular_component | lipid droplet |
A | 0005829 | cellular_component | cytosol |
A | 0005886 | cellular_component | plasma membrane |
A | 0006869 | biological_process | lipid transport |
A | 0008526 | molecular_function | phosphatidylinositol transfer activity |
A | 0008654 | biological_process | phospholipid biosynthetic process |
A | 0009410 | biological_process | response to xenobiotic stimulus |
A | 0015914 | biological_process | phospholipid transport |
A | 0016020 | cellular_component | membrane |
A | 0016126 | biological_process | sterol biosynthetic process |
A | 0032934 | molecular_function | sterol binding |
A | 0042802 | molecular_function | identical protein binding |
A | 0043942 | biological_process | negative regulation of sexual sporulation resulting in formation of a cellular spore |
A | 0071561 | cellular_component | nucleus-vacuole junction |
A | 0071944 | cellular_component | cell periphery |
A | 0120009 | biological_process | intermembrane lipid transfer |
A | 1902556 | cellular_component | phosphatidylinositol transporter complex |
B | 0005737 | cellular_component | cytoplasm |
B | 0005783 | cellular_component | endoplasmic reticulum |
B | 0005789 | cellular_component | endoplasmic reticulum membrane |
B | 0005811 | cellular_component | lipid droplet |
B | 0005829 | cellular_component | cytosol |
B | 0005886 | cellular_component | plasma membrane |
B | 0006869 | biological_process | lipid transport |
B | 0008526 | molecular_function | phosphatidylinositol transfer activity |
B | 0008654 | biological_process | phospholipid biosynthetic process |
B | 0009410 | biological_process | response to xenobiotic stimulus |
B | 0015914 | biological_process | phospholipid transport |
B | 0016020 | cellular_component | membrane |
B | 0016126 | biological_process | sterol biosynthetic process |
B | 0032934 | molecular_function | sterol binding |
B | 0042802 | molecular_function | identical protein binding |
B | 0043942 | biological_process | negative regulation of sexual sporulation resulting in formation of a cellular spore |
B | 0071561 | cellular_component | nucleus-vacuole junction |
B | 0071944 | cellular_component | cell periphery |
B | 0120009 | biological_process | intermembrane lipid transfer |
B | 1902556 | cellular_component | phosphatidylinositol transporter complex |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 401 |
Chain | Residue |
A | TRP84 |
A | ARG92 |
A | ILE185 |
A | ARG236 |
A | GLU330 |
A | ARG334 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A 402 |
Chain | Residue |
A | HOH601 |
A | LEU229 |
A | GLN230 |
A | TYR233 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A 403 |
Chain | Residue |
A | PRO273 |
A | PHE274 |
A | TYR287 |
A | HOH606 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 404 |
Chain | Residue |
A | MET188 |
A | LYS311 |
A | HIS314 |
A | ARG334 |
A | HOH582 |
A | HOH589 |
A | HOH614 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 405 |
Chain | Residue |
A | GLY220 |
A | GLY222 |
A | LYS223 |
B | TRP250 |
B | ASP271 |
site_id | AC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 406 |
Chain | Residue |
A | LYS144 |
A | GLN145 |
A | GLN165 |
A | HOH548 |
B | TRP247 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 407 |
Chain | Residue |
A | THR64 |
A | ASN68 |
A | ASP73 |
A | HOH537 |
A | HOH562 |
B | LYS223 |
site_id | AC8 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE GOL B 401 |
Chain | Residue |
B | TRP84 |
B | CYS89 |
B | ARG92 |
B | ILE185 |
B | ARG236 |
B | GLU330 |
B | ARG334 |
B | HOH505 |
B | HOH644 |
site_id | AC9 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE GOL B 402 |
Chain | Residue |
B | THR243 |
B | TYR287 |
site_id | BC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL B 403 |
Chain | Residue |
A | TRP247 |
B | GLY220 |
B | GLY222 |
B | LYS223 |
site_id | BC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE MG B 404 |
Chain | Residue |
B | TRP84 |
B | TYR93 |
B | HIS232 |
B | PRO234 |
B | HOH505 |
B | HOH547 |
B | HOH548 |
site_id | BC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG B 405 |
Chain | Residue |
B | LYS26 |
B | TYR150 |
B | PHE187 |
B | LYS311 |
B | HOH546 |