4FLM
S-formylglutathione Hydrolase W197I Variant containing Copper
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| A | 0018738 | molecular_function | S-formylglutathione hydrolase activity |
| A | 0046294 | biological_process | formaldehyde catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| B | 0018738 | molecular_function | S-formylglutathione hydrolase activity |
| B | 0046294 | biological_process | formaldehyde catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052689 | molecular_function | carboxylic ester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CU A 301 |
| Chain | Residue |
| A | MET1 |
| A | HIS140 |
| A | HOH454 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CU B 301 |
| Chain | Residue |
| B | MET1 |
| B | HIS140 |
| B | HOH473 |
Functional Information from PROSITE/UniProt
| site_id | PS00120 |
| Number of Residues | 10 |
| Details | LIPASE_SER Lipases, serine active site. VAITGHSMGG |
| Chain | Residue | Details |
| A | VAL155-GLY164 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: Charge relay system => ECO:0000250|UniProtKB:P10768 |
| Chain | Residue | Details |
| A | SDP161 | |
| A | ASP241 | |
| A | HIS276 | |
| B | SDP161 | |
| B | ASP241 | |
| B | HIS276 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22906720, ECO:0007744|PDB:4FLM |
| Chain | Residue | Details |
| A | MET1 | |
| B | MET1 | |
| B | HIS140 | |
| A | HIS140 |
