Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4FL4

Scaffoldin conformation and dynamics revealed by a ternary complex from the Clostridium thermocellum cellulosome

Replaces: 3P0D

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000272	biological_process	polysaccharide catabolic process
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0000272	biological_process	polysaccharide catabolic process
B	0030246	molecular_function	carbohydrate binding
C	0000272	biological_process	polysaccharide catabolic process
C	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
C	0030246	molecular_function	carbohydrate binding
D	0000272	biological_process	polysaccharide catabolic process
D	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
E	0000272	biological_process	polysaccharide catabolic process
E	0030246	molecular_function	carbohydrate binding
F	0000272	biological_process	polysaccharide catabolic process
F	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
F	0030246	molecular_function	carbohydrate binding
G	0000272	biological_process	polysaccharide catabolic process
G	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
H	0000272	biological_process	polysaccharide catabolic process
H	0030246	molecular_function	carbohydrate binding
I	0000272	biological_process	polysaccharide catabolic process
I	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
I	0030246	molecular_function	carbohydrate binding
J	0000272	biological_process	polysaccharide catabolic process
J	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
K	0000272	biological_process	polysaccharide catabolic process
K	0030246	molecular_function	carbohydrate binding
L	0000272	biological_process	polysaccharide catabolic process
L	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
L	0030246	molecular_function	carbohydrate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 101

Chain	Residue
A	ASP24
A	ASN26
A	ASP28
A	LYS30
A	ASN32
A	ASP35

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 102

Chain	Residue
A	ARG66
A	ASP71
A	ASP60
A	ASN62
A	ASP64

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 201

Chain	Residue
B	ALA123
B	GLU125
B	SER126

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 202

Chain	Residue
B	ARG41
B	THR83
B	GLY127

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 203

Chain	Residue
B	LYS24
B	PHE25
B	ASP178

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 204

Chain	Residue
B	LYS86
B	ASN87
C	LYS70

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 205

Chain	Residue
B	THR39
B	ARG41

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 206

Chain	Residue
B	SER141
B	LEU182

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 401

Chain	Residue
C	ASP251
C	VAL253
C	ASP255
C	SER257
C	ASP262

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 402

Chain	Residue
C	ASP284
C	ASN286
C	ASN288
C	ALA290
C	ASP295

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 403

Chain	Residue
C	ARG225
C	PRO244
C	MET246
C	ASP311

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 404

Chain	Residue
C	ARG219
C	ARG287

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 405

Chain	Residue
C	LYS12
C	ARG15

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 406

Chain	Residue
B	LYS86
C	ASN67

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 407

Chain	Residue
C	ASN67
C	PRO68
C	THR69

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 408

Chain	Residue
C	PRO34
C	GLN35

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 409

Chain	Residue
C	LYS112
C	GLU113
C	GLY114

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 101

Chain	Residue
D	ASP24
D	ASN26
D	ASP28
D	LYS30
D	ASP35

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 102

Chain	Residue
D	ASP60
D	ASN62
D	ASP64
D	ARG66
D	ASP71

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 201

Chain	Residue
E	ARG41
E	THR83

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 202

Chain	Residue
E	THR39
E	ARG41
E	ILE128

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 203

Chain	Residue
E	ALA123
E	GLU125
E	SER126

site_id	CC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 E 204

Chain	Residue
E	ASN47

site_id	CC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 205

Chain	Residue
E	THR74
E	SER75

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 206

Chain	Residue
E	LYS86
F	ASN67
F	SO4407

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 207

Chain	Residue
E	SER157
E	GLN176

site_id	CC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA F 401

Chain	Residue
F	ASP284
F	ASN286
F	ASN288
F	ALA290
F	ASP295

site_id	DC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA F 402

Chain	Residue
F	ASP251
F	VAL253
F	ASP255
F	SER257
F	ASP262

site_id	DC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 F 403

Chain	Residue
F	LYS12
F	ARG15

site_id	DC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 404

Chain	Residue
F	ARG225
F	MET246
F	ASP311

site_id	DC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 F 405

Chain	Residue
F	GLY181
F	ARG219

site_id	DC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 F 406

Chain	Residue
F	GLU113

site_id	DC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 407

Chain	Residue
E	LYS86
E	SO4206
F	LYS70

site_id	DC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 408

Chain	Residue
F	ASN67
F	PRO68
F	THR69

site_id	DC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 409

Chain	Residue
F	ASN151
F	PRO153
F	VAL154

site_id	DC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 410

Chain	Residue
D	LEU79
D	ARG81
F	ASP42
F	GLU126

site_id	EC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 F 411

Chain	Residue
F	PRO34
F	GLN35

site_id	EC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 F 412

Chain	Residue
E	LYS86
E	ASN87
E	ASN88
E	ALA89
F	LYS70
F	ASP90

site_id	EC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 413

Chain	Residue
F	ALA272
F	SER276
F	ALA277
F	ASN278

site_id	EC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA G 101

Chain	Residue
G	ASP24
G	ASN26
G	ASP28
G	LYS30
G	ASP35

site_id	EC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA G 102

Chain	Residue
G	ASP60
G	ASN62
G	ASP64
G	ARG66
G	ASN68
G	ASP71

site_id	EC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 H 201

Chain	Residue
H	THR39
H	ARG41

site_id	EC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 H 202

Chain	Residue
H	ARG41
H	THR83
H	ILE128

site_id	EC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 H 203

Chain	Residue
H	ALA123
H	GLU125
H	SER126

site_id	EC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 H 204

Chain	Residue
H	ASN47

site_id	FC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 H 205

Chain	Residue
H	LYS140
H	SER141
H	LEU182

site_id	FC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 H 206

Chain	Residue
H	SER75

site_id	FC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 207

Chain	Residue
H	LYS24
H	PHE25
H	PRO177
H	ASP178

site_id	FC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA I 401

Chain	Residue
I	ASP284
I	ASN286
I	ASN288
I	ALA290
I	ASP295

site_id	FC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA I 402

Chain	Residue
I	ASP251
I	VAL253
I	ASP255
I	SER257
I	ASP262

site_id	FC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 I 403

Chain	Residue
I	ARG225
I	MET246

site_id	FC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 I 404

Chain	Residue
H	LYS86
I	ASN67

site_id	FC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 I 405

Chain	Residue
I	ARG219

site_id	FC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 I 406

Chain	Residue
I	LYS12
I	ARG15

site_id	GC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 I 407

Chain	Residue
I	ASN67
I	PRO68
I	THR69

site_id	GC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 I 408

Chain	Residue
I	ASN7
I	GLN35

site_id	GC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA J 101

Chain	Residue
J	ASP24
J	ASN26
J	ASP28
J	LYS30
J	ASN32
J	ASP35

site_id	GC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA J 102

Chain	Residue
J	ASP60
J	ASN62
J	ASP64
J	ARG66
J	ASP71

site_id	GC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 K 201

Chain	Residue
K	ARG41
K	THR83

site_id	GC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 K 202

Chain	Residue
K	THR39
K	ARG41

site_id	GC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 K 203

Chain	Residue
K	GLY154

site_id	GC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 K 204

Chain	Residue
K	LYS86
K	SO4205
L	ASN67
L	LYS70

site_id	GC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 K 205

Chain	Residue
K	LYS86
K	SO4204
L	ASN67

site_id	HC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 K 206

Chain	Residue
K	LYS24
K	PHE25
K	PRO177
K	ASP178

site_id	HC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 K 207

Chain	Residue
K	SER141

site_id	HC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA L 401

Chain	Residue
L	ASP284
L	ASN286
L	ASN288
L	ALA290
L	ASP295

site_id	HC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA L 402

Chain	Residue
L	ASP251
L	VAL253
L	ASP255
L	SER257
L	ASP262

site_id	HC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 L 403

Chain	Residue
L	LYS112
L	GLU113
L	GLY114

site_id	HC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 L 404

Chain	Residue
L	ARG225
L	MET246
L	ASP311

site_id	HC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 L 405

Chain	Residue
L	ASN67
L	PRO68
L	THR69

site_id	HC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 L 406

Chain	Residue
L	ALA180
L	ARG219
L	ARG287

site_id	HC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 L 407

Chain	Residue
L	THR306
L	SER307
L	SER308

site_id	IC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 L 408

Chain	Residue
L	LYS12
L	GLY14
L	ARG15

site_id	IC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 L 409

Chain	Residue
L	TYR279
L	VAL280
L	GLU281

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DINRNGAINmqDI

Chain	Residue	Details
C	ASP284-ILE296
A	ASP24-LEU36
A	ASP60-VAL72

site_id	PS00448
Number of Residues	20
Details	CLOS_CELLULOSOME_RPT Clostridium cellulosome enzymes repeated domain signature. DIVkDnsINLlDvaeViRcF

Chain	Residue	Details
C	ASP251-PHE270
C	ASP284-PHE303
A	ASP24-VAL43
A	ASP60-LEU79

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)