4FKC

Recombinant prolidase from Thermococcus sibiricus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CD A 401

Chain	Residue
A	ASP240
A	HIS304
A	GLU333
A	GLU347
A	CD402
A	HOH549
A	HOH551

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD A 402

Chain	Residue
A	THR242
A	GLU347
A	CD401
A	HOH549
A	ASP229
A	ASP240

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 403

Chain	Residue
A	GLU366
A	HOH527
A	HOH528
A	HOH529

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 404

Chain	Residue
A	GLU99
A	GLU157
A	HOH530
A	HOH531

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 405

Chain	Residue
A	LEU370
A	CD406
A	HOH544
A	HOH545

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 406

Chain	Residue
A	GLU172
A	CD405

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 407

Chain	Residue
A	ASP195

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site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 408

Chain	Residue
A	HIS2
A	ASP147
A	HOH540
A	HOH541

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site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 409

Chain	Residue
A	HIS3
A	GLU259
A	HOH538
A	HOH539

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site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 410

Chain	Residue
A	GLU75

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site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 411

Chain	Residue
A	ASP7

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Functional Information from PROSITE/UniProt

site_id	PS00491
Number of Residues	13
Details	PROLINE_PEPTIDASE Aminopeptidase P and proline dipeptidase signature. HRTGHgLGIdVHE

Chain	Residue	Details
A	HIS300-GLU312

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