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4FJO

Structure of the Rev1 CTD-Rev3/7-Pol kappa RIR complex

Functional Information from GO Data
ChainGOidnamespacecontents
C0000122biological_processnegative regulation of transcription by RNA polymerase II
C0000785cellular_componentchromatin
C0001558biological_processregulation of cell growth
C0002208biological_processsomatic diversification of immunoglobulins involved in immune response
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005680cellular_componentanaphase-promoting complex
C0005694cellular_componentchromosome
C0005737cellular_componentcytoplasm
C0005819cellular_componentspindle
C0005856cellular_componentcytoskeleton
C0006281biological_processDNA repair
C0006302biological_processdouble-strand break repair
C0007015biological_processactin filament organization
C0008432molecular_functionJUN kinase binding
C0010628biological_processpositive regulation of gene expression
C0010718biological_processpositive regulation of epithelial to mesenchymal transition
C0010719biological_processnegative regulation of epithelial to mesenchymal transition
C0010944biological_processnegative regulation of transcription by competitive promoter binding
C0016035cellular_componentzeta DNA polymerase complex
C0033138biological_processpositive regulation of peptidyl-serine phosphorylation
C0035861cellular_componentsite of double-strand break
C0042177biological_processnegative regulation of protein catabolic process
C0042276biological_processerror-prone translesion synthesis
C0042772biological_processDNA damage response, signal transduction resulting in transcription
C0043247biological_processtelomere maintenance in response to DNA damage
C0045830biological_processpositive regulation of isotype switching
C0045893biological_processpositive regulation of DNA-templated transcription
C0051301biological_processcell division
C0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
C0090090biological_processnegative regulation of canonical Wnt signaling pathway
C1901203biological_processpositive regulation of extracellular matrix assembly
C1904667biological_processnegative regulation of ubiquitin protein ligase activity
C2000042biological_processnegative regulation of double-strand break repair via homologous recombination
C2000048biological_processnegative regulation of cell-cell adhesion mediated by cadherin
C2001034biological_processpositive regulation of double-strand break repair via nonhomologous end joining
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE GOL A 1301
ChainResidue
ALYS1167
ALYS1171
ATYR1210
AARG1213

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE PO4 C 301
ChainResidue
CGLU81
CLYS82
CHIS151
DARG1870
DHIS1873

site_idAC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE PO4 C 302
ChainResidue
AASP1228
AASP1232
CHIS180
CMET181
CHOH403
CHOH458
DARG1870

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE PO4 C 303
ChainResidue
CHIS118
CSER194
CASP195
CILE196

site_idAC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE PO4 C 304
ChainResidue
ALEU1231
AGLN1235
CHIS182
CASP183
CPO4307

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE PO4 C 305
ChainResidue
CMET1
CTYR32
CVAL33
CGLU35
CVAL39
CASP134

site_idAC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE PO4 C 306
ChainResidue
CASN10
CGLU76
CLYS77
CHOH444

site_idAC8
Number of Residues4
DetailsBINDING SITE FOR RESIDUE PO4 C 307
ChainResidue
AVAL1248
CHIS180
CHIS182
CPO4304

site_idAC9
Number of Residues6
DetailsBINDING SITE FOR RESIDUE PO4 C 308
ChainResidue
AGLU1202
AASP1205
AHOH1418
CLYS129
CPRO188
CLEU189

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PDB entries from 2024-07-17

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