4FHP

Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - CaUTP bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016779	molecular_function	nucleotidyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE UTP A 401

Chain	Residue
A	PHE88
A	LYS197
A	SER211
A	TYR212
A	HIS336
A	CA402
A	HOH507
A	HOH508
A	HOH509
A	HOH511
A	HOH523
A	GLY89
A	SER90
A	ASP101
A	ASP103
A	ALA168
A	ASN171
A	THR172
A	LYS193

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 402

Chain	Residue
A	ASP101
A	ASP103
A	UTP401
A	HOH507
A	HOH509

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 403

Chain	Residue
A	TYR122
A	LYS133
A	PHE134
A	TYR348
A	GLY352
A	GLU353

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22608966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22751018","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22885303","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24322298","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4E80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4EP7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NKT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22608966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22885303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EP7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22608966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22885303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EP7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22885303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FHP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22608966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22751018","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22885303","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24322298","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4E80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4EP7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NKU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22608966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22885303","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24322298","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EP7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NKU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22608966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22751018","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22885303","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24322298","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4E80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4EP7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NKT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22608966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22751018","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22885303","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24322298","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4E80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4EP7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NKT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22608966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22751018","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22885303","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24322298","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4E80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4EP7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NKU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22608966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22885303","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24322298","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EP7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NKU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22885303","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FHX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---