Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4FED

Crystal Structure of Htt36Q3H

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0006974	biological_process	DNA damage response
A	0008643	biological_process	carbohydrate transport
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0034219	biological_process	carbohydrate transmembrane transport
A	0034289	biological_process	detection of maltose stimulus
A	0042597	cellular_component	periplasmic space
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0060326	biological_process	cell chemotaxis
A	1901982	molecular_function	maltose binding
A	1990060	cellular_component	maltose transport complex
B	0005515	molecular_function	protein binding
B	0006974	biological_process	DNA damage response
B	0008643	biological_process	carbohydrate transport
B	0015144	molecular_function	carbohydrate transmembrane transporter activity
B	0015768	biological_process	maltose transport
B	0016020	cellular_component	membrane
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0034219	biological_process	carbohydrate transmembrane transport
B	0034289	biological_process	detection of maltose stimulus
B	0042597	cellular_component	periplasmic space
B	0042956	biological_process	maltodextrin transmembrane transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	0060326	biological_process	cell chemotaxis
B	1901982	molecular_function	maltose binding
B	1990060	cellular_component	maltose transport complex
C	0005515	molecular_function	protein binding
C	0006974	biological_process	DNA damage response
C	0008643	biological_process	carbohydrate transport
C	0015144	molecular_function	carbohydrate transmembrane transporter activity
C	0015768	biological_process	maltose transport
C	0016020	cellular_component	membrane
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0034219	biological_process	carbohydrate transmembrane transport
C	0034289	biological_process	detection of maltose stimulus
C	0042597	cellular_component	periplasmic space
C	0042956	biological_process	maltodextrin transmembrane transport
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0055085	biological_process	transmembrane transport
C	0060326	biological_process	cell chemotaxis
C	1901982	molecular_function	maltose binding
C	1990060	cellular_component	maltose transport complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN A 501

Chain	Residue
A	ASP65

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 502

Chain	Residue
A	HIS203
A	CA509
A	HOH605

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 503

Chain	Residue
A	GLU310
A	ZN504
A	HOH607
C	HOH601

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 504

Chain	Residue
A	ZN503
A	GLU310

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN A 506

Chain	Residue
A	LYS1

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN A 507

Chain	Residue
A	HIS39

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 508

Chain	Residue
A	PHE92
A	GLU172

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA A 509

Chain	Residue
A	PRO133
A	ZN502

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 501

Chain	Residue
B	GLU291
C	ASP287
C	GLU310
C	HOH612

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN B 502

Chain	Residue
B	ASP209

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN B 503

Chain	Residue
A	HIS397
B	ASP65

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN B 504

Chain	Residue
B	GLU38

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN B 505

Chain	Residue
B	ASP82

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN B 506

Chain	Residue
B	GLU328
B	HOH608

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN B 508

Chain	Residue
B	TRP158
B	GLU328
B	HOH606

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN B 509

Chain	Residue
A	ARG344
B	HIS395
B	GLN396

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN B 510

Chain	Residue
B	ZN512

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN B 511

Chain	Residue
B	HIS203
B	HOH612

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 512

Chain	Residue
A	GLU278
B	GLU172
B	ZN510
B	HOH607

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN B 513

Chain	Residue
B	LYS170
B	ZN514

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 514

Chain	Residue
A	ASP82
B	LYS170
B	ASP180
B	ZN513

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN C 501

Chain	Residue
B	LYS26
B	ASP30
C	LYS26
C	ASP30
C	ZN510
C	ZN511

site_id	CC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN C 502

Chain	Residue
C	HIS203

site_id	CC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN C 503

Chain	Residue
C	ASP65
C	GLN398

site_id	CC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN C 504

Chain	Residue
A	ASP209
C	SER211

site_id	CC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN C 505

Chain	Residue
C	HIS39

site_id	CC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN C 506

Chain	Residue
C	GLU328

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 507

Chain	Residue
B	ASP287
B	GLU310
C	GLU291
C	HOH612

site_id	DC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN C 508

Chain	Residue
B	LYS26
B	GLU288
C	LYS26
C	GLU288
C	ZN510
C	ZN511

site_id	DC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN C 509

Chain	Residue
C	GLU38

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN C 510

Chain	Residue
B	LYS26
C	ZN501
C	ZN508

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 511

Chain	Residue
B	LYS26
C	LYS26
C	ZN501
C	ZN508

site_id	DC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN C 512

Chain	Residue
A	SER211
B	GLN402
C	ASP209
C	SER211
C	ILE212

site_id	DC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN C 513

Chain	Residue
C	GLU153
C	HIS395
C	GLN401

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO107-ASN124

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	Region: {"description":"Sufficient for interaction with TPR","evidences":[{"source":"PubMed","id":"15654337","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"21685499","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)