4FE3

Structure of murine cytosolic 5'-nucleotidase III complexed with uridinine monophosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005737	cellular_component	cytoplasm
A	0008253	molecular_function	5'-nucleotidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BME A 301

Chain	Residue
A	LYS62
A	ARG63
A	CYS64
A	ASP139
A	MET141

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BME A 302

Chain	Residue
A	CYS34
A	ILE37
A	LYS38

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 303

Chain	Residue
A	GLN155
A	GLU173
A	GLN177
A	HOH554
A	HOH598
A	LYS132

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 304

Chain	Residue
A	ASP49
A	ASN51
A	ASP238
A	U5P305
A	HOH630
A	HOH632

---

site_id	AC5
Number of Residues	23
Details	BINDING SITE FOR RESIDUE U5P A 305

Chain	Residue
A	ASP49
A	PHE50
A	ASN51
A	THR66
A	HIS68
A	ASN69
A	LYS89
A	GLU96
A	TRP113
A	TYR114
A	SER117
A	SER164
A	ALA165
A	GLY166
A	VAL210
A	LYS213
A	MG304
A	HOH401
A	HOH402
A	HOH488
A	HOH534
A	HOH630
A	HOH632

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"16672222","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"16672222","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16672222","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9W197","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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