4FDG

Crystal Structure of an Archaeal MCM Filament

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003697	molecular_function	single-stranded DNA binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0016887	molecular_function	ATP hydrolysis activity
A	0017116	molecular_function	single-stranded DNA helicase activity
A	0042555	cellular_component	MCM complex
A	0042802	molecular_function	identical protein binding
A	0043138	molecular_function	3'-5' DNA helicase activity
B	0003677	molecular_function	DNA binding
B	0003697	molecular_function	single-stranded DNA binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0016887	molecular_function	ATP hydrolysis activity
B	0017116	molecular_function	single-stranded DNA helicase activity
B	0042555	cellular_component	MCM complex
B	0042802	molecular_function	identical protein binding
B	0043138	molecular_function	3'-5' DNA helicase activity
C	0003677	molecular_function	DNA binding
C	0003697	molecular_function	single-stranded DNA binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0016887	molecular_function	ATP hydrolysis activity
C	0017116	molecular_function	single-stranded DNA helicase activity
C	0042555	cellular_component	MCM complex
C	0042802	molecular_function	identical protein binding
C	0043138	molecular_function	3'-5' DNA helicase activity
D	0003677	molecular_function	DNA binding
D	0003697	molecular_function	single-stranded DNA binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0016887	molecular_function	ATP hydrolysis activity
D	0017116	molecular_function	single-stranded DNA helicase activity
D	0042555	cellular_component	MCM complex
D	0042802	molecular_function	identical protein binding
D	0043138	molecular_function	3'-5' DNA helicase activity
E	0003677	molecular_function	DNA binding
E	0003697	molecular_function	single-stranded DNA binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0016887	molecular_function	ATP hydrolysis activity
E	0017116	molecular_function	single-stranded DNA helicase activity
E	0042555	cellular_component	MCM complex
E	0042802	molecular_function	identical protein binding
E	0043138	molecular_function	3'-5' DNA helicase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 701

Chain	Residue
B	HIS144
B	CYS149
B	CYS171
B	CYS174
B	LYS176

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 701

Chain	Residue
A	HIS144
A	CYS149
A	CYS171
A	CYS174

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 701

Chain	Residue
C	HIS144
C	CYS149
C	CYS171
C	CYS174

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 701

Chain	Residue
D	HIS144
D	CYS149
D	CYS171
D	CYS174

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 701

Chain	Residue
E	HIS144
E	CYS149
E	CYS171
E	CYS174

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Motif: {"description":"Walker A","evidences":[{"source":"PROSITE-ProRule","id":"PRU01410","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	15
Details	Motif: {"description":"Walker B","evidences":[{"source":"PROSITE-ProRule","id":"PRU01410","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18417534","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36499022","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VL6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FDG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MII","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	50
Details	Binding site: {"evidences":[{"source":"PubMed","id":"36499022","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31308367","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6MII","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	25
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31308367","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36499022","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6MII","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31308367","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6MII","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	5
Details	Site: {"description":"Arginine finger","evidences":[{"source":"PROSITE-ProRule","id":"PRU01410","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17964268","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---