4FD8

Structure of apo S70C SHV beta-lactamase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030655	biological_process	beta-lactam antibiotic catabolic process
A	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE MA4 A 301

Chain	Residue
A	ARG93
A	ALA284
A	ILE287
A	MA4302
A	HOH405
A	HOH446
A	HOH454
A	HOH481
A	HOH584
A	HOH602
A	HOH613
A	ILE95
A	HOH618
A	HOH639
A	HIS96
A	VAL224
A	PRO226
A	ALA248
A	VAL261
A	ILE263
A	ALA280

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MA4 A 302

Chain	Residue
A	MA4301

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile; acyl-ester intermediate => ECO:0000250|UniProtKB:A0A5R8T042, ECO:0000255|PROSITE-ProRule:PRU10101

Chain	Residue	Details
A	CYS70

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton acceptor

Chain	Residue	Details
A	GLU168

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site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250|UniProtKB:A0A5R8T042

Chain	Residue	Details
A	SER130
A	GLU166
A	LYS73

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