4FBU

Dpo4 polymerase pre-insertion binary complex with the N-(deoxyguanosin-8-yl)-1-aminopyrene lesion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0009432	biological_process	SOS response
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006281	biological_process	DNA repair
B	0006974	biological_process	DNA damage response
B	0009432	biological_process	SOS response
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0042276	biological_process	error-prone translesion synthesis
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 401

Chain	Residue
A	ASP7
A	ASP105
A	GLU106
P	DC14

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 402

Chain	Residue
A	ASP7
A	PHE8
A	ASP105

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 401

Chain	Residue
B	GLU106
B	CA402
B	HOH510
D	DC14
B	ASP7
B	ASP105

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 402

Chain	Residue
B	ASP7
B	PHE8
B	ASP105
B	CA401
B	HOH520
B	HOH558

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE:

Chain	Residue	Details
A	GLU106
B	GLU106

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
A	ASP7
A	ASP105
B	ASP7
B	ASP105

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site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Substrate discrimination

Chain	Residue	Details
A	TYR12
B	TYR12

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