4FBC

Structure of mutant RIP from barley seeds in complex with AMP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0016787	molecular_function	hydrolase activity
A	0017148	biological_process	negative regulation of translation
A	0030598	molecular_function	rRNA N-glycosylase activity
A	0031640	biological_process	killing of cells of another organism
A	0035821	biological_process	modulation of process of another organism
A	0050832	biological_process	defense response to fungus
A	0090729	molecular_function	toxin activity
B	0005737	cellular_component	cytoplasm
B	0016787	molecular_function	hydrolase activity
B	0017148	biological_process	negative regulation of translation
B	0030598	molecular_function	rRNA N-glycosylase activity
B	0031640	biological_process	killing of cells of another organism
B	0035821	biological_process	modulation of process of another organism
B	0050832	biological_process	defense response to fungus
B	0090729	molecular_function	toxin activity
C	0005737	cellular_component	cytoplasm
C	0016787	molecular_function	hydrolase activity
C	0017148	biological_process	negative regulation of translation
C	0030598	molecular_function	rRNA N-glycosylase activity
C	0031640	biological_process	killing of cells of another organism
C	0035821	biological_process	modulation of process of another organism
C	0050832	biological_process	defense response to fungus
C	0090729	molecular_function	toxin activity
D	0005737	cellular_component	cytoplasm
D	0016787	molecular_function	hydrolase activity
D	0017148	biological_process	negative regulation of translation
D	0030598	molecular_function	rRNA N-glycosylase activity
D	0031640	biological_process	killing of cells of another organism
D	0035821	biological_process	modulation of process of another organism
D	0050832	biological_process	defense response to fungus
D	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE AMP A 301

Chain	Residue
A	TYR87
A	LEU88
A	GLU89
A	LEU170
A	ARG178
A	HOH499
A	HOH521
A	HOH590
A	HOH769

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AMP B 301

Chain	Residue
B	TYR87
B	LEU88
B	GLU89
B	LEU170
B	ARG178
B	HOH481
B	HOH490
B	HOH567
B	HOH810
B	HOH847
C	ARG119

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AMP C 301

Chain	Residue
C	TYR87
C	LEU88
C	GLU89
C	GLY116
C	LEU170
C	ARG178
C	HOH441
C	HOH603
C	HOH751
C	HOH894
C	HOH918

---

site_id	AC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE AMP D 301

Chain	Residue
A	ARG119
D	TYR87
D	LEU88
D	GLY116
D	THR117
D	LEU170
D	ARG178
D	HOH452
D	HOH500
D	HOH513
D	HOH526
D	HOH546
D	HOH549
D	HOH596
D	HOH721
D	HOH776

---

Functional Information from PROSITE/UniProt

site_id	PS00275
Number of Residues	17
Details	SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. LlMVnEATRFQtVSgfV

Chain	Residue	Details
A	LEU170-VAL186

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: ACT_SITE => ECO:0000250

Chain	Residue	Details
A	GLU175
B	GLU175
C	GLU175
D	GLU175

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N-acetylalanine => ECO:0000250

Chain	Residue	Details
A	ALA2
B	ALA2
C	ALA2
D	ALA2

---