Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0008270 | molecular_function | zinc ion binding |
| C | 0004672 | molecular_function | protein kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006468 | biological_process | protein phosphorylation |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ADP A 601 |
| Chain | Residue |
| A | GLY67 |
| A | HIS139 |
| A | SER181 |
| A | ASN182 |
| A | LEU184 |
| A | ASP196 |
| A | MG602 |
| A | HOH701 |
| A | HOH702 |
| A | HOH705 |
| A | HOH712 |
| A | SER70 |
| A | HOH734 |
| A | VAL72 |
| A | ALA88 |
| A | LYS90 |
| A | MET118 |
| A | PRO135 |
| A | TYR136 |
| A | LEU137 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 602 |
| Chain | Residue |
| A | ASN182 |
| A | ASP196 |
| A | ADP601 |
| A | HOH701 |
| A | HOH702 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 401 |
| Chain | Residue |
| B | CYS296 |
| B | CYS299 |
| B | HIS309 |
| B | HIS315 |
| site_id | AC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ADP C 601 |
| Chain | Residue |
| C | ILE64 |
| C | GLY67 |
| C | SER70 |
| C | VAL72 |
| C | ALA88 |
| C | LYS90 |
| C | MET118 |
| C | MET134 |
| C | PRO135 |
| C | TYR136 |
| C | LEU137 |
| C | HIS139 |
| C | SER181 |
| C | ASN182 |
| C | LEU184 |
| C | ASP196 |
| C | MG602 |
| C | HOH701 |
| C | HOH702 |
| C | HOH703 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 602 |
| Chain | Residue |
| C | ASN182 |
| C | ASP196 |
| C | ADP601 |
| C | HOH701 |
| C | HOH702 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 401 |
| Chain | Residue |
| D | CYS296 |
| D | CYS299 |
| D | HIS309 |
| D | HIS315 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 27 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGEGTFSSVYlAtaqlqvgpeek.......IALK |
| Chain | Residue | Details |
| A | ILE64-LYS90 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IvHrDVKpsNFLY |
| Chain | Residue | Details |
| A | ILE173-TYR185 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00600","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
