4F5X

Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0019013	cellular_component	viral nucleocapsid
A	0019028	cellular_component	viral capsid
A	0039616	cellular_component	T=2 icosahedral viral capsid
A	0039625	cellular_component	viral inner capsid
A	0044423	cellular_component	virion component
B	0003723	molecular_function	RNA binding
B	0019013	cellular_component	viral nucleocapsid
B	0019028	cellular_component	viral capsid
B	0039616	cellular_component	T=2 icosahedral viral capsid
B	0039625	cellular_component	viral inner capsid
B	0044423	cellular_component	virion component
C	0005198	molecular_function	structural molecule activity
C	0019028	cellular_component	viral capsid
C	0019031	cellular_component	viral envelope
C	0019064	biological_process	fusion of virus membrane with host plasma membrane
C	0039621	cellular_component	T=13 icosahedral viral capsid
C	0039626	cellular_component	viral intermediate capsid
C	0044423	cellular_component	virion component
C	0044650	biological_process	adhesion of symbiont to host cell
C	0046789	molecular_function	host cell surface receptor binding
C	0046872	molecular_function	metal ion binding
D	0005198	molecular_function	structural molecule activity
D	0019028	cellular_component	viral capsid
D	0019031	cellular_component	viral envelope
D	0019064	biological_process	fusion of virus membrane with host plasma membrane
D	0039621	cellular_component	T=13 icosahedral viral capsid
D	0039626	cellular_component	viral intermediate capsid
D	0044423	cellular_component	virion component
D	0044650	biological_process	adhesion of symbiont to host cell
D	0046789	molecular_function	host cell surface receptor binding
D	0046872	molecular_function	metal ion binding
E	0005198	molecular_function	structural molecule activity
E	0019028	cellular_component	viral capsid
E	0019031	cellular_component	viral envelope
E	0019064	biological_process	fusion of virus membrane with host plasma membrane
E	0039621	cellular_component	T=13 icosahedral viral capsid
E	0039626	cellular_component	viral intermediate capsid
E	0044423	cellular_component	virion component
E	0044650	biological_process	adhesion of symbiont to host cell
E	0046789	molecular_function	host cell surface receptor binding
E	0046872	molecular_function	metal ion binding
F	0005198	molecular_function	structural molecule activity
F	0019028	cellular_component	viral capsid
F	0019031	cellular_component	viral envelope
F	0019064	biological_process	fusion of virus membrane with host plasma membrane
F	0039621	cellular_component	T=13 icosahedral viral capsid
F	0039626	cellular_component	viral intermediate capsid
F	0044423	cellular_component	virion component
F	0044650	biological_process	adhesion of symbiont to host cell
F	0046789	molecular_function	host cell surface receptor binding
F	0046872	molecular_function	metal ion binding
G	0005198	molecular_function	structural molecule activity
G	0019028	cellular_component	viral capsid
G	0019031	cellular_component	viral envelope
G	0019064	biological_process	fusion of virus membrane with host plasma membrane
G	0039621	cellular_component	T=13 icosahedral viral capsid
G	0039626	cellular_component	viral intermediate capsid
G	0044423	cellular_component	virion component
G	0044650	biological_process	adhesion of symbiont to host cell
G	0046789	molecular_function	host cell surface receptor binding
G	0046872	molecular_function	metal ion binding
H	0005198	molecular_function	structural molecule activity
H	0019028	cellular_component	viral capsid
H	0019031	cellular_component	viral envelope
H	0019064	biological_process	fusion of virus membrane with host plasma membrane
H	0039621	cellular_component	T=13 icosahedral viral capsid
H	0039626	cellular_component	viral intermediate capsid
H	0044423	cellular_component	virion component
H	0044650	biological_process	adhesion of symbiont to host cell
H	0046789	molecular_function	host cell surface receptor binding
H	0046872	molecular_function	metal ion binding
I	0005198	molecular_function	structural molecule activity
I	0019028	cellular_component	viral capsid
I	0019031	cellular_component	viral envelope
I	0019064	biological_process	fusion of virus membrane with host plasma membrane
I	0039621	cellular_component	T=13 icosahedral viral capsid
I	0039626	cellular_component	viral intermediate capsid
I	0044423	cellular_component	virion component
I	0044650	biological_process	adhesion of symbiont to host cell
I	0046789	molecular_function	host cell surface receptor binding
I	0046872	molecular_function	metal ion binding
J	0005198	molecular_function	structural molecule activity
J	0019028	cellular_component	viral capsid
J	0019031	cellular_component	viral envelope
J	0019064	biological_process	fusion of virus membrane with host plasma membrane
J	0039621	cellular_component	T=13 icosahedral viral capsid
J	0039626	cellular_component	viral intermediate capsid
J	0044423	cellular_component	virion component
J	0044650	biological_process	adhesion of symbiont to host cell
J	0046789	molecular_function	host cell surface receptor binding
J	0046872	molecular_function	metal ion binding
K	0005198	molecular_function	structural molecule activity
K	0019028	cellular_component	viral capsid
K	0019031	cellular_component	viral envelope
K	0019064	biological_process	fusion of virus membrane with host plasma membrane
K	0039621	cellular_component	T=13 icosahedral viral capsid
K	0039626	cellular_component	viral intermediate capsid
K	0044423	cellular_component	virion component
K	0044650	biological_process	adhesion of symbiont to host cell
K	0046789	molecular_function	host cell surface receptor binding
K	0046872	molecular_function	metal ion binding
L	0005198	molecular_function	structural molecule activity
L	0019028	cellular_component	viral capsid
L	0019031	cellular_component	viral envelope
L	0019064	biological_process	fusion of virus membrane with host plasma membrane
L	0039621	cellular_component	T=13 icosahedral viral capsid
L	0039626	cellular_component	viral intermediate capsid
L	0044423	cellular_component	virion component
L	0044650	biological_process	adhesion of symbiont to host cell
L	0046789	molecular_function	host cell surface receptor binding
L	0046872	molecular_function	metal ion binding
M	0005198	molecular_function	structural molecule activity
M	0019028	cellular_component	viral capsid
M	0019031	cellular_component	viral envelope
M	0019064	biological_process	fusion of virus membrane with host plasma membrane
M	0039621	cellular_component	T=13 icosahedral viral capsid
M	0039626	cellular_component	viral intermediate capsid
M	0044423	cellular_component	virion component
M	0044650	biological_process	adhesion of symbiont to host cell
M	0046789	molecular_function	host cell surface receptor binding
M	0046872	molecular_function	metal ion binding
N	0005198	molecular_function	structural molecule activity
N	0019028	cellular_component	viral capsid
N	0019031	cellular_component	viral envelope
N	0019064	biological_process	fusion of virus membrane with host plasma membrane
N	0039621	cellular_component	T=13 icosahedral viral capsid
N	0039626	cellular_component	viral intermediate capsid
N	0044423	cellular_component	virion component
N	0044650	biological_process	adhesion of symbiont to host cell
N	0046789	molecular_function	host cell surface receptor binding
N	0046872	molecular_function	metal ion binding
O	0005198	molecular_function	structural molecule activity
O	0019028	cellular_component	viral capsid
O	0019031	cellular_component	viral envelope
O	0019064	biological_process	fusion of virus membrane with host plasma membrane
O	0039621	cellular_component	T=13 icosahedral viral capsid
O	0039626	cellular_component	viral intermediate capsid
O	0044423	cellular_component	virion component
O	0044650	biological_process	adhesion of symbiont to host cell
O	0046789	molecular_function	host cell surface receptor binding
O	0046872	molecular_function	metal ion binding
W	0000166	molecular_function	nucleotide binding
W	0001172	biological_process	RNA-templated transcription
W	0003723	molecular_function	RNA binding
W	0003968	molecular_function	RNA-directed RNA polymerase activity
W	0006351	biological_process	DNA-templated transcription
W	0016740	molecular_function	transferase activity
W	0016779	molecular_function	nucleotidyltransferase activity
W	0019079	biological_process	viral genome replication
W	0034062	molecular_function	5'-3' RNA polymerase activity
W	0044423	cellular_component	virion component

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN C 401

Chain	Residue
C	HIS153
D	HIS153
E	HIS153

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN F 401

Chain	Residue
F	HIS153
G	HIS153
H	HIS153

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN I 401

Chain	Residue
I	HIS153
J	HIS153
K	HIS153

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN L 401

Chain	Residue
L	HIS153
M	HIS153
N	HIS153

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	143
Details	Region: {"description":"Interaction with the inner capsid protein VP2","evidences":[{"source":"HAMAP-Rule","id":"MF_04129","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	39
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04129","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---