4F4E

Crystal structure of Aromatic-amino-acid aminotransferase from Burkholderia pseudomallei covalently bound to pyridoxal phosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004838	molecular_function	L-tyrosine-2-oxoglutarate transaminase activity
A	0005829	cellular_component	cytosol
A	0006520	biological_process	amino acid metabolic process
A	0008483	molecular_function	transaminase activity
A	0009058	biological_process	biosynthetic process
A	0016740	molecular_function	transferase activity
A	0030170	molecular_function	pyridoxal phosphate binding
A	0033585	biological_process	L-phenylalanine biosynthetic process from chorismate via phenylpyruvate
A	0042802	molecular_function	identical protein binding
A	0170034	biological_process	L-amino acid biosynthetic process
A	0170038	biological_process	proteinogenic amino acid biosynthetic process
B	0003824	molecular_function	catalytic activity
B	0004838	molecular_function	L-tyrosine-2-oxoglutarate transaminase activity
B	0005829	cellular_component	cytosol
B	0006520	biological_process	amino acid metabolic process
B	0008483	molecular_function	transaminase activity
B	0009058	biological_process	biosynthetic process
B	0016740	molecular_function	transferase activity
B	0030170	molecular_function	pyridoxal phosphate binding
B	0033585	biological_process	L-phenylalanine biosynthetic process from chorismate via phenylpyruvate
B	0042802	molecular_function	identical protein binding
B	0170034	biological_process	L-amino acid biosynthetic process
B	0170038	biological_process	proteinogenic amino acid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 500

Chain	Residue
A	TYR149
A	TYR151
A	LEU179
A	HIS180
A	HOH625
A	HOH710

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 501

Chain	Residue
A	ARG376
A	HOH760
A	TRP132
A	ASN185
A	PHE350

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 500

Chain	Residue
B	TYR149
B	TYR151
B	LEU179
B	HIS180
B	HOH655

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 501

Chain	Residue
B	TRP132
B	ASN185
B	ARG376
B	HOH814
B	HOH1013

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Functional Information from PROSITE/UniProt

site_id	PS00105
Number of Residues	14
Details	AA_TRANSFER_CLASS_1 Aminotransferases class-I pyridoxal-phosphate attachment site. SFSKsfSLyGERVG

Chain	Residue	Details
A	SER245-GLY258

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