4F36

Crystal structure of Nucleoside diphosphate kinase B from Trypanosoma brucei, apo form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0006183	biological_process	GTP biosynthetic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0010608	biological_process	post-transcriptional regulation of gene expression
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0097014	cellular_component	ciliary plasm
B	0000166	molecular_function	nucleotide binding
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0006183	biological_process	GTP biosynthetic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0010608	biological_process	post-transcriptional regulation of gene expression
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0097014	cellular_component	ciliary plasm
C	0000166	molecular_function	nucleotide binding
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0006183	biological_process	GTP biosynthetic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0010608	biological_process	post-transcriptional regulation of gene expression
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0097014	cellular_component	ciliary plasm
D	0000166	molecular_function	nucleotide binding
D	0004550	molecular_function	nucleoside diphosphate kinase activity
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0006183	biological_process	GTP biosynthetic process
D	0006228	biological_process	UTP biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
D	0010608	biological_process	post-transcriptional regulation of gene expression
D	0016301	molecular_function	kinase activity
D	0016740	molecular_function	transferase activity
D	0097014	cellular_component	ciliary plasm
E	0000166	molecular_function	nucleotide binding
E	0004550	molecular_function	nucleoside diphosphate kinase activity
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0006183	biological_process	GTP biosynthetic process
E	0006228	biological_process	UTP biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0010608	biological_process	post-transcriptional regulation of gene expression
E	0016301	molecular_function	kinase activity
E	0016740	molecular_function	transferase activity
E	0097014	cellular_component	ciliary plasm
F	0000166	molecular_function	nucleotide binding
F	0004550	molecular_function	nucleoside diphosphate kinase activity
F	0005524	molecular_function	ATP binding
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0006183	biological_process	GTP biosynthetic process
F	0006228	biological_process	UTP biosynthetic process
F	0006241	biological_process	CTP biosynthetic process
F	0010608	biological_process	post-transcriptional regulation of gene expression
F	0016301	molecular_function	kinase activity
F	0016740	molecular_function	transferase activity
F	0097014	cellular_component	ciliary plasm

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SCN F 201

Chain	Residue
F	LYS33
F	SER143

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Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NvcHGSDSV

Chain	Residue	Details
A	ASN114-VAL122

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