4F2P
Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with diEtglycol-thio-DADMe-Immucillin-A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
| A | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0009164 | biological_process | nucleoside catabolic process |
| A | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
| B | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0009164 | biological_process | nucleoside catabolic process |
| B | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 2EL A 301 |
| Chain | Residue |
| A | ILE50 |
| A | GLU174 |
| A | SER196 |
| A | ASP197 |
| A | PHE207 |
| A | HOH412 |
| A | HOH531 |
| B | PHE105 |
| A | SER76 |
| A | ALA77 |
| A | GLY78 |
| A | ALA150 |
| A | PHE151 |
| A | ILE152 |
| A | GLU172 |
| A | MET173 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 302 |
| Chain | Residue |
| A | GLY154 |
| A | SER155 |
| A | ASP200 |
| A | GLN201 |
| A | HOH432 |
| A | HOH552 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 303 |
| Chain | Residue |
| A | SER131 |
| A | ARG134 |
| B | ASP93 |
| B | ARG142 |
| B | HOH501 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 304 |
| Chain | Residue |
| A | PHE105 |
| A | GLY106 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 2EL B 301 |
| Chain | Residue |
| A | PHE105 |
| A | TYR107 |
| B | ILE50 |
| B | SER76 |
| B | ALA77 |
| B | GLY78 |
| B | ALA150 |
| B | PHE151 |
| B | ILE152 |
| B | GLU172 |
| B | MET173 |
| B | GLU174 |
| B | SER196 |
| B | ASP197 |
| B | PHE207 |
| B | ASP208 |
| B | HOH402 |
| B | HOH522 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 302 |
| Chain | Residue |
| B | SER206 |
| B | PHE210 |
| B | HOH417 |
| B | HOH444 |
| B | HOH534 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 303 |
| Chain | Residue |
| A | GLY114 |
| B | GLY30 |
| B | HOH403 |
| B | HOH414 |
| B | HOH447 |
| B | HOH504 |
