Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4F2N

Crystal structure of iron superoxide dismutase from Leishmania major

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004784	molecular_function	superoxide dismutase activity
A	0005739	cellular_component	mitochondrion
A	0006801	biological_process	superoxide metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0019430	biological_process	removal of superoxide radicals
A	0046872	molecular_function	metal ion binding
B	0004784	molecular_function	superoxide dismutase activity
B	0005739	cellular_component	mitochondrion
B	0006801	biological_process	superoxide metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0019430	biological_process	removal of superoxide radicals
B	0046872	molecular_function	metal ion binding
C	0004784	molecular_function	superoxide dismutase activity
C	0005739	cellular_component	mitochondrion
C	0006801	biological_process	superoxide metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0019430	biological_process	removal of superoxide radicals
C	0046872	molecular_function	metal ion binding
D	0004784	molecular_function	superoxide dismutase activity
D	0005739	cellular_component	mitochondrion
D	0006801	biological_process	superoxide metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0019430	biological_process	removal of superoxide radicals
D	0046872	molecular_function	metal ion binding
E	0004784	molecular_function	superoxide dismutase activity
E	0005739	cellular_component	mitochondrion
E	0006801	biological_process	superoxide metabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0019430	biological_process	removal of superoxide radicals
E	0046872	molecular_function	metal ion binding
F	0004784	molecular_function	superoxide dismutase activity
F	0005739	cellular_component	mitochondrion
F	0006801	biological_process	superoxide metabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0019430	biological_process	removal of superoxide radicals
F	0046872	molecular_function	metal ion binding
G	0004784	molecular_function	superoxide dismutase activity
G	0005739	cellular_component	mitochondrion
G	0006801	biological_process	superoxide metabolic process
G	0016491	molecular_function	oxidoreductase activity
G	0019430	biological_process	removal of superoxide radicals
G	0046872	molecular_function	metal ion binding
H	0004784	molecular_function	superoxide dismutase activity
H	0005739	cellular_component	mitochondrion
H	0006801	biological_process	superoxide metabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0019430	biological_process	removal of superoxide radicals
H	0046872	molecular_function	metal ion binding
I	0004784	molecular_function	superoxide dismutase activity
I	0005739	cellular_component	mitochondrion
I	0006801	biological_process	superoxide metabolic process
I	0016491	molecular_function	oxidoreductase activity
I	0019430	biological_process	removal of superoxide radicals
I	0046872	molecular_function	metal ion binding
J	0004784	molecular_function	superoxide dismutase activity
J	0005739	cellular_component	mitochondrion
J	0006801	biological_process	superoxide metabolic process
J	0016491	molecular_function	oxidoreductase activity
J	0019430	biological_process	removal of superoxide radicals
J	0046872	molecular_function	metal ion binding
K	0004784	molecular_function	superoxide dismutase activity
K	0005739	cellular_component	mitochondrion
K	0006801	biological_process	superoxide metabolic process
K	0016491	molecular_function	oxidoreductase activity
K	0019430	biological_process	removal of superoxide radicals
K	0046872	molecular_function	metal ion binding
L	0004784	molecular_function	superoxide dismutase activity
L	0005739	cellular_component	mitochondrion
L	0006801	biological_process	superoxide metabolic process
L	0016491	molecular_function	oxidoreductase activity
L	0019430	biological_process	removal of superoxide radicals
L	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 A 300

Chain	Residue
A	HIS58
A	HIS108
A	ASP191
A	HIS195
A	HOH401

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 B 300

Chain	Residue
B	HOH483
B	HIS58
B	HIS108
B	ASP191
B	HIS195

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 C 300

Chain	Residue
C	HIS58
C	HIS108
C	ASP191
C	HIS195
C	HOH402

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 D 300

Chain	Residue
D	HIS58
D	HIS108
D	ASP191
D	HIS195
D	HOH401

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 E 300

Chain	Residue
E	HIS58
E	HIS108
E	ASP191
E	HIS195
E	HOH401

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 F 300

Chain	Residue
F	HIS58
F	HIS108
F	ASP191
F	HIS195
F	HOH435

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 G 300

Chain	Residue
G	HIS58
G	HIS108
G	ASP191
G	HIS195
G	HOH459

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 H 300

Chain	Residue
H	HIS58
H	HIS108
H	ASP191
H	HIS195
H	HOH401

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 I 300

Chain	Residue
I	HIS58
I	HIS108
I	ASP191
I	HIS195
I	HOH401

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 J 300

Chain	Residue
J	HIS58
J	HIS108
J	ASP191
J	HIS195
J	HOH404

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 K 300

Chain	Residue
K	HIS58
K	HIS108
K	ASP191
K	HIS195
K	HOH428

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 L 300

Chain	Residue
L	HIS58
L	HIS108
L	ASP191
L	HIS195
L	HOH432

Functional Information from PROSITE/UniProt

site_id	PS00088
Number of Residues	8
Details	SOD_MN Manganese and iron superoxide dismutases signature. DvWEHAYY

Chain	Residue	Details
A	ASP191-TYR198

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)