4EXQ

CRYSTAL STRUCTURE of UROPORPHYRINOGEN DECARBOXYLASE (UPD) FROM BURKHOLDERIA THAILANDENSIS E264

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004853	molecular_function	uroporphyrinogen decarboxylase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006778	biological_process	porphyrin-containing compound metabolic process
A	0006779	biological_process	porphyrin-containing compound biosynthetic process
A	0006782	biological_process	protoporphyrinogen IX biosynthetic process
A	0006783	biological_process	heme biosynthetic process
A	0016831	molecular_function	carboxy-lyase activity
A	0019353	biological_process	protoporphyrinogen IX biosynthetic process from glutamate

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 401

Chain	Residue
A	THR9
A	THR19
A	ASP20
A	PRO307

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Functional Information from PROSITE/UniProt

site_id	PS00906
Number of Residues	10
Details	UROD_1 Uroporphyrinogen decarboxylase signature 1. PIWLMRQAGR

Chain	Residue	Details
A	PRO23-ARG32

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site_id	PS00907
Number of Residues	17
Details	UROD_2 Uroporphyrinogen decarboxylase signature 2. IGFSGsPWTLacYmv.EG

Chain	Residue	Details
A	ILE148-GLY164

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00218

Chain	Residue	Details
A	ARG28
A	ASP78
A	TYR160
A	THR215
A	HIS333

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00218

Chain	Residue	Details
A	ASP78

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