4EX5

Crystal structure of lysyl-tRNA synthetase LysRS from Burkholderia thailandensis bound to lysine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0003676	molecular_function	nucleic acid binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004824	molecular_function	lysine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006430	biological_process	lysyl-tRNA aminoacylation
A	0016874	molecular_function	ligase activity
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
B	0000049	molecular_function	tRNA binding
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0003676	molecular_function	nucleic acid binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004824	molecular_function	lysine-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006412	biological_process	translation
B	0006418	biological_process	tRNA aminoacylation for protein translation
B	0006430	biological_process	lysyl-tRNA aminoacylation
B	0016874	molecular_function	ligase activity
B	0042803	molecular_function	protein homodimerization activity
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE LYS A 601

Chain	Residue
A	GLY216
A	GLY479
A	HOH750
A	HOH759
A	GLU240
A	ARG262
A	GLU278
A	TYR280
A	ASN428
A	PHE430
A	GLU432
A	GLY477

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE LYS B 601

Chain	Residue
B	GLY216
B	GLU240
B	ARG262
B	GLU278
B	TYR280
B	ASN428
B	PHE430
B	GLU432
B	GLY477
B	GLY479
B	HOH721

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00252","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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