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4EWV

Crystal structure of GH3.12 in complex with AMPCPP

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0006952biological_processdefense response
A0009626biological_processplant-type hypersensitive response
A0009863biological_processsalicylic acid mediated signaling pathway
A0010112biological_processregulation of systemic acquired resistance
A0016046biological_processdetection of fungus
A0016874molecular_functionligase activity
A0016881molecular_functionacid-amino acid ligase activity
A0018874biological_processbenzoate metabolic process
A0034052biological_processpositive regulation of plant-type hypersensitive response
A0042742biological_processdefense response to bacterium
A0052625molecular_functionN-(4-aminobenzoyl)-L-glutamate synthetase activity
A0052626molecular_functionN-benzoyl-L-glutamate synthetase activity
A0052627molecular_functionN-vanillate-L-glutamate synthetase activity
A0052628molecular_functionN-(4-hydroxybenzoyl)-L-glutamate synthetase activity
A0071456biological_processcellular response to hypoxia
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0006952biological_processdefense response
B0009626biological_processplant-type hypersensitive response
B0009863biological_processsalicylic acid mediated signaling pathway
B0010112biological_processregulation of systemic acquired resistance
B0016046biological_processdetection of fungus
B0016874molecular_functionligase activity
B0016881molecular_functionacid-amino acid ligase activity
B0018874biological_processbenzoate metabolic process
B0034052biological_processpositive regulation of plant-type hypersensitive response
B0042742biological_processdefense response to bacterium
B0052625molecular_functionN-(4-aminobenzoyl)-L-glutamate synthetase activity
B0052626molecular_functionN-benzoyl-L-glutamate synthetase activity
B0052627molecular_functionN-vanillate-L-glutamate synthetase activity
B0052628molecular_functionN-(4-hydroxybenzoyl)-L-glutamate synthetase activity
B0071456biological_processcellular response to hypoxia
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE APC A 601
ChainResidue
AVAL299
ATYR325
AGLY326
ASER327
ATYR347
AASP398
APHE414
ALYS550
AMN602

site_idAC2
Number of Residues1
DetailsBINDING SITE FOR RESIDUE MN A 602
ChainResidue
AAPC601

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE APC B 601
ChainResidue
ASER80
BTYR325
BGLY326
BSER328
BLYS550

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsBINDING: BINDING => ECO:0000269|PubMed:22628555, ECO:0007744|PDB:4EPM, ECO:0007744|PDB:4EQ4, ECO:0007744|PDB:4EQL
ChainResidueDetails
ASER95
BSER328
BTYR347
BASP398
ATHR301
ATHR324
ASER328
ATYR347
AASP398
BSER95
BTHR301
BTHR324

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:22628555, ECO:0007744|PDB:4EQ4, ECO:0007744|PDB:4EQL
ChainResidueDetails
ATYR120
BTYR120

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:22628555, ECO:0007744|PDB:4EQ4
ChainResidueDetails
AARG417
BARG417

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PDB entries from 2025-06-18

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