4EWL
Crystal Structure of MshB with glycerol and Acetate bound in the active site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0010125 | biological_process | mycothiol biosynthetic process |
| A | 0016137 | biological_process | glycoside metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| A | 0019213 | molecular_function | deacetylase activity |
| A | 0035595 | molecular_function | N-acetylglucosaminylinositol deacetylase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0010125 | biological_process | mycothiol biosynthetic process |
| B | 0016137 | biological_process | glycoside metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| B | 0019213 | molecular_function | deacetylase activity |
| B | 0035595 | molecular_function | N-acetylglucosaminylinositol deacetylase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PE4 A 401 |
| Chain | Residue |
| A | TYR67 |
| B | HOH769 |
| A | GLY70 |
| A | HOH615 |
| A | HOH786 |
| B | TYR67 |
| B | GLY70 |
| B | ARG77 |
| B | PE4408 |
| B | HOH705 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | ALA33 |
| A | GLN34 |
| A | VAL35 |
| A | HIS36 |
| A | GLY80 |
| A | SER82 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 403 |
| Chain | Residue |
| A | HIS13 |
| A | ASP16 |
| A | HIS147 |
| A | ACT404 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 404 |
| Chain | Residue |
| A | HIS13 |
| A | ASP15 |
| A | ASP16 |
| A | TYR142 |
| A | HIS147 |
| A | ZN403 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 405 |
| Chain | Residue |
| A | HIS13 |
| A | GLY43 |
| A | GLU45 |
| A | GLY46 |
| A | ARG68 |
| A | ASP95 |
| A | GLY97 |
| A | MET98 |
| A | HIS144 |
| A | HOH617 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 406 |
| Chain | Residue |
| A | VAL177 |
| A | PRO178 |
| A | GLY277 |
| A | GLY278 |
| A | HOH636 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 407 |
| Chain | Residue |
| A | ASP291 |
| A | ALA294 |
| A | GLY295 |
| A | LEU296 |
| A | GLY297 |
| A | HOH694 |
| A | HOH697 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 401 |
| Chain | Residue |
| B | HIS13 |
| B | ASP16 |
| B | HIS147 |
| B | ACT402 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT B 402 |
| Chain | Residue |
| B | HIS13 |
| B | ASP15 |
| B | ASP16 |
| B | TYR142 |
| B | HIS147 |
| B | ZN401 |
| B | HOH770 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 403 |
| Chain | Residue |
| B | HIS13 |
| B | GLY43 |
| B | GLY46 |
| B | ARG68 |
| B | ASP95 |
| B | GLY97 |
| B | HIS144 |
| B | HOH770 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 404 |
| Chain | Residue |
| B | ALA33 |
| B | GLN34 |
| B | VAL35 |
| B | HIS36 |
| B | GLY80 |
| B | VAL81 |
| B | SER82 |
| B | HOH535 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 405 |
| Chain | Residue |
| B | VAL158 |
| B | VAL177 |
| B | PRO178 |
| B | GLY277 |
| B | GLY278 |
| B | HOH702 |
| B | HOH709 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 406 |
| Chain | Residue |
| B | ALA282 |
| B | ALA294 |
| B | GLY295 |
| B | GLY297 |
| B | HOH654 |
| B | HOH720 |
| B | HOH746 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 407 |
| Chain | Residue |
| B | ARG6 |
| B | GLU127 |
| B | ARG129 |
| B | ASP220 |
| B | ARG286 |
| site_id | BC6 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PE4 B 408 |
| Chain | Residue |
| B | SER82 |
| B | ALA83 |
| B | PRO84 |
| B | ILE85 |
| B | TYR86 |
| B | GLY88 |
| B | GLY89 |
| B | GLU285 |
| B | HOH534 |
| B | HOH551 |
| B | HOH598 |
| B | HOH600 |
| B | HOH662 |
| B | HOH706 |
| A | ARG52 |
| A | TRP53 |
| A | PE4401 |
| A | HOH527 |
| B | ARG77 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12958317 |
| Chain | Residue | Details |
| A | HIS13 | |
| A | ASP16 | |
| A | HIS147 | |
| B | HIS13 | |
| B | ASP16 | |
| B | HIS147 |
