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Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4EVA

Crystal Structure of Mouse Catenin beta-59 in 5.6M urea

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007155	biological_process	cell adhesion
A	0045296	molecular_function	cadherin binding
C	0007155	biological_process	cell adhesion
C	0045296	molecular_function	cadherin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE URE A 701

Chain	Residue
A	THR330
A	TYR331
A	HOH811
A	HOH813
C	THR330
C	TYR331

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE A 702

Chain	Residue
A	HOH1078
A	THR332
A	ASP372
A	HOH970

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE URE A 703

Chain	Residue
A	ARG474
A	LEU644
A	HIS645
A	SER646
A	ALA652
A	HOH1163

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE URE A 704

Chain	Residue
A	LEU286
A	ASN287
A	LYS288
A	TYR331
A	HOH829
A	HOH917
A	HOH1101

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE URE A 705

Chain	Residue
A	THR289
A	ASN290
A	VAL291
A	URE711
A	HOH908
C	THR330
C	THR332

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE URE A 706

Chain	Residue
A	VAL358
A	GLU359
A	ALA360
A	GLY361
A	GLN395
A	URE715

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE URE A 707

Chain	Residue
A	LYS625
A	GLU629

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE URE A 708

Chain	Residue
A	CYS429
A	ASN430
A	LYS435
A	HIS470
A	SER473
A	ARG474
A	HOH930

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE A 709

Chain	Residue
A	LEU244
A	GLY245
A	SER246
A	LEU252
A	LYS288

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE A 710

Chain	Residue
A	ASP249
A	LYS288
A	THR289
A	ASN290
A	HOH1152

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE URE A 711

Chain	Residue
A	THR289
A	ASN290
A	URE705
A	HOH979
A	HOH1182
C	ARG329

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE A 712

Chain	Residue
A	SER250
A	PHE253
A	TYR254

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE URE A 713

Chain	Residue
A	LEU313
A	SER352

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE A 714

Chain	Residue
A	ALA356
A	GLU359
A	HOH1198

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE A 715

Chain	Residue
A	GLN322
A	GLU359
A	URE706
A	HOH1065

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE URE A 716

Chain	Residue
A	LYS394
A	GLN395
A	ASN431
A	LYS433
A	ASN434
A	URE723
A	HOH918

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE URE A 717

Chain	Residue
A	LEU368
A	THR371
A	ASP372
A	HOH820
A	HOH935
A	HOH945
C	LYS292
C	URE701

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE URE A 718

Chain	Residue
A	GLU399
A	MET437

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE URE A 719

Chain	Residue
A	SER411
A	HOH1196

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE A 720

Chain	Residue
A	PRO373
A	SER374
A	GLN375
A	HOH824

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE URE A 721

Chain	Residue
A	LYS345
A	HOH905

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE A 722

Chain	Residue
A	GLN407
A	HOH1087
A	THR371

site_id	CC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE URE A 723

Chain	Residue
A	GLN395
A	GLY397
A	MET398
A	GLU399
A	ASN434
A	MET437
A	URE716

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE A 724

Chain	Residue
A	PRO501
A	ARG542
A	HOH814

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE A 725

Chain	Residue
A	SER502
A	ILE507
A	URE726
A	HOH895

site_id	CC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE A 726

Chain	Residue
A	HIS503
A	TRP504
A	URE725

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE A 727

Chain	Residue
A	GLU568
A	GLU571
A	URE728
A	HOH881

site_id	DC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE URE A 728

Chain	Residue
A	ARG515
A	GLU571
A	GLY575
A	ARG612
A	VAL613
A	URE727
A	HOH1009

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE A 729

Chain	Residue
A	LEU519
A	ARG582
A	HOH1116
A	HOH1143

site_id	DC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE A 730

Chain	Residue
A	ARG582
A	GLU620
A	URE733

site_id	DC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE URE A 731

Chain	Residue
A	ARG515
A	HOH860

site_id	DC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE A 732

Chain	Residue
A	ARG582
A	ASP583
A	VAL584
A	URE734
A	HOH882

site_id	DC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE A 733

Chain	Residue
A	ARG582
A	GLN623
A	URE730
A	URE734
A	HOH882

site_id	DC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE URE A 734

Chain	Residue
A	PRO521
A	HIS524
A	ARG582
A	URE732
A	URE733
A	HOH912
A	HOH1113

site_id	DC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE A 735

Chain	Residue
A	LEU603
A	TYR604
A	PRO639
A	GLU642

site_id	DC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE A 736

Chain	Residue
A	TYR604
A	PRO606
A	HOH1170

site_id	EC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE A 737

Chain	Residue
A	PRO606
A	GLU608
A	HOH835

site_id	EC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE A 738

Chain	Residue
A	VAL600
A	TYR604
A	GLU634
A	GLY635

site_id	EC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE URE C 701

Chain	Residue
A	THR332
A	URE717
C	VAL291
C	LYS292
C	TYR333
C	HOH859
C	HOH903

site_id	EC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE URE C 702

Chain	Residue
A	ARG329
C	THR289
C	ASN290
C	URE706
C	HOH942
C	HOH1037
C	HOH1068

site_id	EC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE URE C 703

Chain	Residue
C	THR332
C	GLU334
C	ASP372
C	HOH809
C	HOH901
C	HOH1075

site_id	EC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE C 704

Chain	Residue
C	ARG474
C	LEU644
C	HIS645
C	SER646
C	ALA652

site_id	EC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE C 705

Chain	Residue
C	LEU286
C	ASN287
C	LYS288
C	TYR331
C	HOH808

site_id	EC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE URE C 706

Chain	Residue
A	THR330
A	THR332
C	THR289
C	ASN290
C	VAL291
C	URE702
C	HOH859

site_id	EC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE C 707

Chain	Residue
C	VAL358
C	GLU359
C	ALA360
C	GLY361
C	GLN395

site_id	FC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE C 708

Chain	Residue
C	VAL349
C	GLU629
C	HOH991

site_id	FC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE URE C 709

Chain	Residue
C	CYS429
C	ASN430
C	LYS435
C	HIS470
C	SER473
C	ARG474
C	URE723
C	HOH874
C	HOH888

site_id	FC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE URE C 710

Chain	Residue
C	GLU163

site_id	FC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE C 711

Chain	Residue
C	HIS176
C	GLY216
C	HIS219
C	ASN220
C	TYR254

site_id	FC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE URE C 712

Chain	Residue
C	GLY245

site_id	FC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE C 713

Chain	Residue
C	GLN322
C	ASN326
C	ARG329
C	HOH1011

site_id	FC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE C 714

Chain	Residue
C	VAL349
C	SER351
C	LYS354

site_id	FC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE URE C 715

Chain	Residue
A	LYS292
C	LEU368
C	THR371
C	ASP372
C	HOH826
C	HOH911
C	HOH1019

site_id	FC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE URE C 716

Chain	Residue
C	GLN375
C	SER411

site_id	GC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE C 717

Chain	Residue
C	PRO373
C	SER374
C	GLN375
C	HOH833

site_id	GC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE URE C 718

Chain	Residue
C	MET437
C	VAL441

site_id	GC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE C 719

Chain	Residue
C	PRO492
C	LYS496
C	GLN530
C	GLN538
C	HOH878

site_id	GC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE URE C 720

Chain	Residue
C	ARG542
C	HOH835

site_id	GC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE C 721

Chain	Residue
C	HIS503
C	TRP504
C	PRO505
C	HOH1000
C	HOH1067

site_id	GC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE URE C 722

Chain	Residue
C	ARG469

site_id	GC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE C 723

Chain	Residue
C	ARG474
C	URE709
C	HOH888

site_id	GC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE URE C 724

Chain	Residue
C	ARG528
C	GLU529
C	HOH846
C	HOH956
C	HOH977
C	HOH977

site_id	GC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE URE C 725

Chain	Residue
C	ARG549

site_id	HC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE URE C 726

Chain	Residue
C	ASP546
C	ARG549

site_id	HC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE URE C 727

Chain	Residue
C	HIS544
C	GLN548
C	GLN601
C	LEU602
C	SER605
C	HOH872

site_id	HC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE C 728

Chain	Residue
C	ARG582
C	ARG587
C	GLU620
C	GLN623
C	HOH864

site_id	HC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE C 729

Chain	Residue
C	VAL584
C	ARG591
C	ASP624

site_id	HC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE C 730

Chain	Residue
C	PRO606
C	ILE607
C	GLU608
C	HOH871

site_id	HC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE URE C 731

Chain	Residue
C	ARG515
C	GLY575
C	HIS578
C	ILE579
C	ARG612
C	HOH825

site_id	HC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE URE C 732

Chain	Residue
C	LEU659
C	PHE660
C	MET662

site_id	HC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE URE C 733

Chain	Residue
C	GLU267
C	LYS270
C	ALA633
C	GLU634
C	HOH1054

site_id	HC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE URE C 734

Chain	Residue
C	ALA656
C	ALA657
C	PHE660
C	HOH967

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphotyrosine; by FYN and PTK6 => ECO:0000269\|PubMed:12640114

Chain	Residue	Details
A	TYR142
C	TYR142

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17242355, ECO:0007744\|PubMed:21183079

Chain	Residue	Details
A	SER191
C	SER191

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphoserine; by CDK5 => ECO:0000250\|UniProtKB:P35222

Chain	Residue	Details
A	SER246
C	SER246

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0000250\|UniProtKB:P35222

Chain	Residue	Details
A	TYR331
A	TYR333
C	TYR331
C	TYR333

site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphoserine; by AMPK => ECO:0000269\|PubMed:20361929, ECO:0007744\|PubMed:17242355

Chain	Residue	Details
A	SER552
C	SER552

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0000250\|UniProtKB:P35222

Chain	Residue	Details
A	THR556
C	THR556

site_id	SWS_FT_FI7
Number of Residues	2
Details	MOD_RES: S-nitrosocysteine => ECO:0000269\|PubMed:20705246

Chain	Residue	Details
A	CYS619
C	CYS619

219140

PDB entries from 2024-05-01

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