4EUD
Succinyl-CoA:acetate CoA-transferase (AarC) in complex with CoA and citrate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006083 | biological_process | acetate metabolic process |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| A | 0008410 | molecular_function | CoA-transferase activity |
| A | 0008775 | molecular_function | acetate CoA-transferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| A | 0045733 | biological_process | acetate catabolic process |
| A | 1901289 | biological_process | succinyl-CoA catabolic process |
| B | 0006083 | biological_process | acetate metabolic process |
| B | 0006084 | biological_process | acetyl-CoA metabolic process |
| B | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| B | 0008410 | molecular_function | CoA-transferase activity |
| B | 0008775 | molecular_function | acetate CoA-transferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| B | 0045733 | biological_process | acetate catabolic process |
| B | 1901289 | biological_process | succinyl-CoA catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE COA A 2598 |
| Chain | Residue |
| A | GLN267 |
| A | GLY385 |
| A | ILE386 |
| A | SER389 |
| A | ALA407 |
| A | LYS408 |
| A | ILE412 |
| A | HOH518 |
| A | HOH546 |
| A | HOH618 |
| A | HOH623 |
| A | GLY269 |
| A | HOH662 |
| A | HOH777 |
| A | HOH941 |
| A | HOH953 |
| A | HOH1117 |
| A | HOH1132 |
| A | HOH1199 |
| A | HOH1217 |
| A | HOH1256 |
| B | LYS240 |
| A | GLU294 |
| A | ASN361 |
| A | MET363 |
| A | ILE364 |
| A | SER374 |
| A | MET383 |
| A | ASN384 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 515 |
| Chain | Residue |
| A | ASN112 |
| A | ARG120 |
| A | ASN125 |
| B | GLY443 |
| B | HOH681 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 516 |
| Chain | Residue |
| A | VAL196 |
| A | ARG354 |
| A | HOH1017 |
| B | ARG354 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE COA B 2598 |
| Chain | Residue |
| B | GLN267 |
| B | GLY269 |
| B | ASN361 |
| B | MET363 |
| B | ILE364 |
| B | VAL377 |
| B | MET383 |
| B | ASN384 |
| B | GLY385 |
| B | ILE386 |
| B | SER389 |
| B | ALA407 |
| B | LYS408 |
| B | ILE412 |
| B | HOH518 |
| B | HOH582 |
| B | HOH642 |
| B | HOH673 |
| B | HOH802 |
| B | HOH945 |
| B | HOH1018 |
| B | HOH1058 |
| B | HOH1163 |
| B | HOH1166 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CIT B 2502 |
| Chain | Residue |
| B | THR36 |
| B | SER71 |
| B | THR94 |
| B | ARG228 |
| B | PRO231 |
| B | HOH520 |
| B | HOH955 |
| B | HOH1128 |
| B | HOH1161 |
| B | HOH1201 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 515 |
| Chain | Residue |
| A | GLY443 |
| B | ASN112 |
| B | ARG120 |
| B | ASN125 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 516 |
| Chain | Residue |
| A | ARG354 |
| B | VAL196 |
| B | ARG354 |
| B | HOH755 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: 5-glutamyl coenzyme A thioester intermediate => ECO:0000269|PubMed:23030530 |
| Chain | Residue | Details |
| A | GLU294 | |
| B | GLU294 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23030530 |
| Chain | Residue | Details |
| A | GLY269 | |
| B | LYS408 | |
| A | ILE364 | |
| A | ASN384 | |
| A | GLY388 | |
| A | LYS408 | |
| B | GLY269 | |
| B | ILE364 | |
| B | ASN384 | |
| B | GLY388 |
