4EUB
Succinyl-CoA:acetate CoA-transferase (AarCH6-E294A) in complex with CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006083 | biological_process | acetate metabolic process |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| A | 0008410 | molecular_function | CoA-transferase activity |
| A | 0008775 | molecular_function | acetate CoA-transferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| A | 0045733 | biological_process | acetate catabolic process |
| A | 1901289 | biological_process | succinyl-CoA catabolic process |
| B | 0006083 | biological_process | acetate metabolic process |
| B | 0006084 | biological_process | acetyl-CoA metabolic process |
| B | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| B | 0008410 | molecular_function | CoA-transferase activity |
| B | 0008775 | molecular_function | acetate CoA-transferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| B | 0045733 | biological_process | acetate catabolic process |
| B | 1901289 | biological_process | succinyl-CoA catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE COA A 2598 |
| Chain | Residue |
| A | GLN267 |
| A | ASN384 |
| A | GLY385 |
| A | ILE386 |
| A | GLY388 |
| A | SER389 |
| A | ALA407 |
| A | ILE412 |
| A | HOH517 |
| A | HOH518 |
| A | HOH527 |
| A | VAL270 |
| A | HOH530 |
| A | HOH566 |
| A | HOH569 |
| A | HOH585 |
| A | HOH593 |
| A | HOH598 |
| A | HOH605 |
| A | HOH645 |
| A | HOH653 |
| A | HOH683 |
| A | GLY271 |
| A | HOH789 |
| A | HOH812 |
| A | HOH868 |
| A | HOH1166 |
| A | HOH1231 |
| A | HOH1256 |
| B | LYS240 |
| A | ASN272 |
| A | VAL273 |
| A | ASN361 |
| A | MET363 |
| A | ILE364 |
| A | MET383 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 515 |
| Chain | Residue |
| A | ASN112 |
| A | ARG120 |
| A | ASN125 |
| A | HOH1168 |
| B | GLY443 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 516 |
| Chain | Residue |
| A | VAL196 |
| A | ARG354 |
| A | HOH858 |
| B | ARG354 |
| site_id | AC4 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE COA B 2598 |
| Chain | Residue |
| B | GLN267 |
| B | VAL270 |
| B | GLY271 |
| B | ASN272 |
| B | VAL273 |
| B | ASN361 |
| B | MET363 |
| B | ILE364 |
| B | MET383 |
| B | ASN384 |
| B | GLY385 |
| B | ILE386 |
| B | SER389 |
| B | ALA407 |
| B | LYS408 |
| B | HOH518 |
| B | HOH531 |
| B | HOH553 |
| B | HOH573 |
| B | HOH574 |
| B | HOH582 |
| B | HOH584 |
| B | HOH608 |
| B | HOH631 |
| B | HOH639 |
| B | HOH652 |
| B | HOH726 |
| B | HOH743 |
| B | HOH748 |
| B | HOH797 |
| B | HOH954 |
| B | HOH1092 |
| B | HOH1165 |
| B | HOH1227 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 515 |
| Chain | Residue |
| A | GLY443 |
| A | HOH695 |
| B | ASN112 |
| B | ARG120 |
| B | ASN125 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 516 |
| Chain | Residue |
| B | VAL196 |
| B | ARG354 |
| B | HOH744 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: 5-glutamyl coenzyme A thioester intermediate => ECO:0000269|PubMed:23030530 |
| Chain | Residue | Details |
| A | ALA294 | |
| B | ALA294 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23030530 |
| Chain | Residue | Details |
| A | GLY269 | |
| B | LYS408 | |
| A | ILE364 | |
| A | ASN384 | |
| A | GLY388 | |
| A | LYS408 | |
| B | GLY269 | |
| B | ILE364 | |
| B | ASN384 | |
| B | GLY388 |
