4EU9
Succinyl-CoA:acetate CoA-transferase (AarCH6-R228E) in complex with CoA and a covalent glutamyl-CoA thioester adduct
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003986 | molecular_function | acetyl-CoA hydrolase activity |
| A | 0006083 | biological_process | acetate metabolic process |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| A | 0008410 | molecular_function | CoA-transferase activity |
| A | 0008775 | molecular_function | acetate CoA-transferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| A | 0045733 | biological_process | acetate catabolic process |
| A | 1901289 | biological_process | succinyl-CoA catabolic process |
| B | 0003986 | molecular_function | acetyl-CoA hydrolase activity |
| B | 0006083 | biological_process | acetate metabolic process |
| B | 0006084 | biological_process | acetyl-CoA metabolic process |
| B | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| B | 0008410 | molecular_function | CoA-transferase activity |
| B | 0008775 | molecular_function | acetate CoA-transferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| B | 0045733 | biological_process | acetate catabolic process |
| B | 1901289 | biological_process | succinyl-CoA catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 39 |
| Details | BINDING SITE FOR RESIDUE COA A 2598 |
| Chain | Residue |
| A | GLN267 |
| A | ASN384 |
| A | GLY385 |
| A | ILE386 |
| A | SER389 |
| A | ALA407 |
| A | LYS408 |
| A | ILE412 |
| A | HOH518 |
| A | HOH521 |
| A | HOH535 |
| A | GLY269 |
| A | HOH566 |
| A | HOH581 |
| A | HOH588 |
| A | HOH748 |
| A | HOH774 |
| A | HOH806 |
| A | HOH807 |
| A | HOH857 |
| A | HOH992 |
| A | HOH1102 |
| A | GLU294 |
| A | HOH1280 |
| A | HOH1382 |
| A | HOH1450 |
| A | HOH1496 |
| A | HOH1565 |
| B | GLU237 |
| B | LYS240 |
| B | HOH1326 |
| B | HOH1524 |
| B | HOH1613 |
| A | ASN361 |
| A | GLY362 |
| A | MET363 |
| A | ILE364 |
| A | SER374 |
| A | MET383 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 515 |
| Chain | Residue |
| A | ASN112 |
| A | ARG120 |
| A | ASN125 |
| B | GLY443 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 516 |
| Chain | Residue |
| A | VAL196 |
| A | ARG354 |
| A | HOH1287 |
| B | ARG354 |
| site_id | AC4 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE COA B 2598 |
| Chain | Residue |
| B | GLN267 |
| B | GLU294 |
| B | ASN361 |
| B | MET363 |
| B | ILE364 |
| B | ASN384 |
| B | GLY385 |
| B | ILE386 |
| B | GLY388 |
| B | SER389 |
| B | ALA407 |
| B | LYS408 |
| B | ILE412 |
| B | HOH517 |
| B | HOH518 |
| B | HOH530 |
| B | HOH554 |
| B | HOH572 |
| B | HOH587 |
| B | HOH687 |
| B | HOH830 |
| B | HOH838 |
| B | HOH881 |
| B | HOH925 |
| B | HOH1024 |
| B | HOH1177 |
| B | HOH1320 |
| B | HOH1513 |
| B | HOH1577 |
| B | HOH1609 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 515 |
| Chain | Residue |
| A | GLY443 |
| B | ASN112 |
| B | ARG120 |
| B | ASN125 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 516 |
| Chain | Residue |
| A | HOH1501 |
| B | VAL196 |
| B | ARG354 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"5-glutamyl coenzyme A thioester intermediate","evidences":[{"source":"PubMed","id":"23030530","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23030530","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
