4EU7
Succinyl-CoA:acetate CoA-transferase (AarCH6) in complex with CoA and citrate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006083 | biological_process | acetate metabolic process |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| A | 0008410 | molecular_function | CoA-transferase activity |
| A | 0008775 | molecular_function | acetate CoA-transferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| A | 0045733 | biological_process | acetate catabolic process |
| A | 1901289 | biological_process | succinyl-CoA catabolic process |
| B | 0006083 | biological_process | acetate metabolic process |
| B | 0006084 | biological_process | acetyl-CoA metabolic process |
| B | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| B | 0008410 | molecular_function | CoA-transferase activity |
| B | 0008775 | molecular_function | acetate CoA-transferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| B | 0045733 | biological_process | acetate catabolic process |
| B | 1901289 | biological_process | succinyl-CoA catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE COA A 2598 |
| Chain | Residue |
| A | GLN267 |
| A | ILE386 |
| A | SER389 |
| A | ALA407 |
| A | LYS408 |
| A | ILE412 |
| A | HOH518 |
| A | HOH522 |
| A | HOH528 |
| A | HOH554 |
| A | HOH555 |
| A | GLY269 |
| A | HOH593 |
| A | HOH694 |
| A | HOH747 |
| A | HOH925 |
| A | HOH959 |
| A | HOH977 |
| A | HOH1006 |
| A | HOH1040 |
| A | HOH1183 |
| A | HOH1238 |
| A | GLU294 |
| A | HOH1366 |
| A | HOH1416 |
| A | HOH1611 |
| B | LYS240 |
| B | HOH1210 |
| B | HOH1245 |
| B | HOH1447 |
| A | ASN361 |
| A | MET363 |
| A | ILE364 |
| A | MET383 |
| A | ASN384 |
| A | GLY385 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CIT A 2502 |
| Chain | Residue |
| A | THR36 |
| A | SER71 |
| A | PHE92 |
| A | THR94 |
| A | ARG228 |
| A | ALA230 |
| A | VAL270 |
| A | HOH520 |
| A | HOH1177 |
| A | HOH1204 |
| A | HOH1254 |
| A | HOH1340 |
| A | HOH1527 |
| A | HOH1587 |
| A | HOH1692 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 515 |
| Chain | Residue |
| A | ASN112 |
| A | ARG120 |
| A | ASN125 |
| B | GLY443 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 516 |
| Chain | Residue |
| A | VAL196 |
| A | ARG354 |
| A | HOH1068 |
| B | ARG354 |
| site_id | AC5 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE COA B 2598 |
| Chain | Residue |
| B | GLN267 |
| B | GLY269 |
| B | GLU294 |
| B | ASN361 |
| B | MET363 |
| B | ILE364 |
| B | ASN384 |
| B | GLY385 |
| B | ILE386 |
| B | SER389 |
| B | ALA407 |
| B | LYS408 |
| B | ILE412 |
| B | HOH518 |
| B | HOH596 |
| B | HOH605 |
| B | HOH630 |
| B | HOH636 |
| B | HOH725 |
| B | HOH727 |
| B | HOH827 |
| B | HOH891 |
| B | HOH989 |
| B | HOH1048 |
| B | HOH1072 |
| B | HOH1228 |
| B | HOH1441 |
| B | HOH1457 |
| B | HOH1746 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CIT B 2502 |
| Chain | Residue |
| B | HOH1304 |
| B | HOH1506 |
| B | THR36 |
| B | SER71 |
| B | PHE92 |
| B | THR94 |
| B | ARG228 |
| B | PRO231 |
| B | HOH520 |
| B | HOH937 |
| B | HOH947 |
| B | HOH1039 |
| B | HOH1063 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 515 |
| Chain | Residue |
| A | GLY443 |
| B | ASN112 |
| B | ARG120 |
| B | ASN125 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 516 |
| Chain | Residue |
| A | ARG354 |
| A | HOH1356 |
| B | VAL196 |
| B | ARG354 |
| B | HOH831 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: 5-glutamyl coenzyme A thioester intermediate => ECO:0000269|PubMed:23030530 |
| Chain | Residue | Details |
| A | GLU294 | |
| B | GLU294 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23030530 |
| Chain | Residue | Details |
| A | GLY269 | |
| B | LYS408 | |
| A | ILE364 | |
| A | ASN384 | |
| A | GLY388 | |
| A | LYS408 | |
| B | GLY269 | |
| B | ILE364 | |
| B | ASN384 | |
| B | GLY388 |
