4EU4
Succinyl-CoA: acetate CoA-transferase (AarCH6) in complex with CoA (hexagonal lattice)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003986 | molecular_function | acetyl-CoA hydrolase activity |
| A | 0006083 | biological_process | acetate metabolic process |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| A | 0008410 | molecular_function | CoA-transferase activity |
| A | 0008775 | molecular_function | acetate CoA-transferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| A | 0045733 | biological_process | acetate catabolic process |
| A | 1901289 | biological_process | succinyl-CoA catabolic process |
| B | 0003986 | molecular_function | acetyl-CoA hydrolase activity |
| B | 0006083 | biological_process | acetate metabolic process |
| B | 0006084 | biological_process | acetyl-CoA metabolic process |
| B | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| B | 0008410 | molecular_function | CoA-transferase activity |
| B | 0008775 | molecular_function | acetate CoA-transferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| B | 0045733 | biological_process | acetate catabolic process |
| B | 1901289 | biological_process | succinyl-CoA catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE COA A 2598 |
| Chain | Residue |
| A | GLY269 |
| A | MET383 |
| A | ASN384 |
| A | GLY385 |
| A | ILE386 |
| A | SER389 |
| A | ALA407 |
| A | LYS408 |
| A | ILE412 |
| A | HOH518 |
| A | HOH544 |
| A | VAL270 |
| A | HOH547 |
| A | HOH550 |
| A | HOH616 |
| A | HOH653 |
| A | SO4818 |
| A | VAL273 |
| A | GLU294 |
| A | ASN361 |
| A | MET363 |
| A | ILE364 |
| A | SER374 |
| A | VAL377 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 816 |
| Chain | Residue |
| A | ARG200 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 817 |
| Chain | Residue |
| A | HIS252 |
| A | GLN256 |
| A | ARG258 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 818 |
| Chain | Residue |
| A | ALA407 |
| A | LYS408 |
| A | GLY409 |
| A | COA2598 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 819 |
| Chain | Residue |
| A | PRO460 |
| A | ARG463 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 823 |
| Chain | Residue |
| A | THR2 |
| A | ARG4 |
| A | PRO174 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 824 |
| Chain | Residue |
| A | ARG11 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 829 |
| Chain | Residue |
| A | MET175 |
| A | ARG335 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 830 |
| Chain | Residue |
| A | ARG101 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 832 |
| Chain | Residue |
| A | TRP171 |
| A | ARG226 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 834 |
| Chain | Residue |
| A | ARG6 |
| A | THR140 |
| A | GLU141 |
| A | ASP142 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 515 |
| Chain | Residue |
| A | ASN112 |
| A | ARG120 |
| A | ASN125 |
| B | GLY443 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 516 |
| Chain | Residue |
| A | VAL196 |
| A | ARG354 |
| A | HOH614 |
| B | HOH755 |
| site_id | BC5 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE COA B 2598 |
| Chain | Residue |
| B | GLY269 |
| B | VAL270 |
| B | GLY271 |
| B | VAL273 |
| B | GLU294 |
| B | ILE364 |
| B | SER374 |
| B | VAL377 |
| B | MET383 |
| B | ASN384 |
| B | GLY385 |
| B | ILE386 |
| B | SER389 |
| B | ALA407 |
| B | LYS408 |
| B | ILE412 |
| B | HOH518 |
| B | HOH707 |
| B | HOH726 |
| B | HOH790 |
| B | HOH794 |
| B | SO4826 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 820 |
| Chain | Residue |
| B | THR2 |
| B | ARG4 |
| B | PRO174 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 821 |
| Chain | Residue |
| B | VAL8 |
| B | ARG11 |
| site_id | BC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 822 |
| Chain | Residue |
| B | ARG101 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 825 |
| Chain | Residue |
| B | ARG200 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 826 |
| Chain | Residue |
| B | ALA407 |
| B | LYS408 |
| B | COA2598 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 827 |
| Chain | Residue |
| B | HIS252 |
| B | GLN256 |
| B | ARG258 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 828 |
| Chain | Residue |
| B | PRO460 |
| B | ARG463 |
| site_id | CC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 831 |
| Chain | Residue |
| B | MET175 |
| B | ARG335 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 833 |
| Chain | Residue |
| B | TRP171 |
| B | ARG226 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 835 |
| Chain | Residue |
| B | ASP142 |
| B | ARG6 |
| B | THR140 |
| B | GLU141 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 515 |
| Chain | Residue |
| A | GLY443 |
| B | ASN112 |
| B | ARG120 |
| B | ASN125 |
| site_id | CC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 516 |
| Chain | Residue |
| B | VAL196 |
| B | ARG354 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"5-glutamyl coenzyme A thioester intermediate","evidences":[{"source":"PubMed","id":"23030530","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23030530","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
