4EU1
Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004021 | molecular_function | L-alanine:2-oxoglutarate transaminase activity |
| A | 0004069 | molecular_function | L-aspartate:2-oxoglutarate transaminase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0020023 | cellular_component | kinetoplast |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0031981 | cellular_component | nuclear lumen |
| A | 0033353 | biological_process | L-methionine cycle |
| A | 0097014 | cellular_component | ciliary plasm |
| B | 0004021 | molecular_function | L-alanine:2-oxoglutarate transaminase activity |
| B | 0004069 | molecular_function | L-aspartate:2-oxoglutarate transaminase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0020023 | cellular_component | kinetoplast |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0031981 | cellular_component | nuclear lumen |
| B | 0033353 | biological_process | L-methionine cycle |
| B | 0097014 | cellular_component | ciliary plasm |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 400 |
| Chain | Residue |
| A | HIS244 |
| A | PRO278 |
| A | LEU279 |
| A | TYR280 |
| B | HIS244 |
| B | PRO278 |
| B | LEU279 |
| B | TYR280 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 401 |
| Chain | Residue |
| A | ARG185 |
| A | PHE217 |
| B | VAL326 |
| A | HIS181 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 402 |
| Chain | Residue |
| A | ARG315 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 403 |
| Chain | Residue |
| A | TYR30 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 404 |
| Chain | Residue |
| A | LYS145 |
| A | ASP328 |
| A | TRP329 |
| A | HIS331 |
| A | THR342 |
| A | GLY343 |
| A | HOH650 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 401 |
| Chain | Residue |
| A | VAL326 |
| B | HIS181 |
| B | ARG185 |
| B | PHE217 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 402 |
| Chain | Residue |
| B | ARG315 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 403 |
| Chain | Residue |
| B | LYS145 |
| B | ASP328 |
| B | TRP329 |
| B | THR342 |
| B | GLY343 |
