4ESX
Crystal structure of C. albicans Thi5 complexed with PLP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009228 | biological_process | thiamine biosynthetic process |
| A | 0009229 | biological_process | thiamine diphosphate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0106344 | molecular_function | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP |
| B | 0009228 | biological_process | thiamine biosynthetic process |
| B | 0009229 | biological_process | thiamine diphosphate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0106344 | molecular_function | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Motif: {"description":"CCCFC; essential for catalytic activity, may be the site of iron coordination","evidences":[{"source":"UniProtKB","id":"P43534","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"22568620","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22568620","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"22568620","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
