4ERC

Structure of VHZ bound to metavanadate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004721	molecular_function	phosphoprotein phosphatase activity
A	0004722	molecular_function	protein serine/threonine phosphatase activity
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006470	biological_process	protein dephosphorylation
A	0008138	molecular_function	protein tyrosine/serine/threonine phosphatase activity
A	0016311	biological_process	dephosphorylation
A	0016787	molecular_function	hydrolase activity
A	0016791	molecular_function	phosphatase activity
A	0060271	biological_process	cilium assembly
B	0004721	molecular_function	phosphoprotein phosphatase activity
B	0004722	molecular_function	protein serine/threonine phosphatase activity
B	0004725	molecular_function	protein tyrosine phosphatase activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006470	biological_process	protein dephosphorylation
B	0008138	molecular_function	protein tyrosine/serine/threonine phosphatase activity
B	0016311	biological_process	dephosphorylation
B	0016787	molecular_function	hydrolase activity
B	0016791	molecular_function	phosphatase activity
B	0060271	biological_process	cilium assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE VN4 A 201

Chain	Residue
A	ARG60
A	GLU134
A	HOH302
A	ASP65
A	CYS95
A	ALA96
A	LEU97
A	GLY98
A	PHE99
A	GLY100
A	ARG101

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE VN4 B 201

Chain	Residue
B	ASP65
B	CYS95
B	ALA96
B	LEU97
B	GLY98
B	PHE99
B	GLY100
B	ARG101
B	GLU134
B	HOH368
B	HOH422

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Functional Information from PROSITE/UniProt

site_id	PS00383
Number of Residues	11
Details	TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCalGfgRTG

Chain	Residue	Details
A	VAL93-GLY103

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	286
Details	Domain: {"description":"Tyrosine-protein phosphatase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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