Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4EQV

Structure of Saccharomyces cerevisiae invertase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000324	cellular_component	fungal-type vacuole
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0004564	molecular_function	beta-fructofuranosidase activity
A	0004575	molecular_function	sucrose alpha-glucosidase activity
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005975	biological_process	carbohydrate metabolic process
A	0005987	biological_process	sucrose catabolic process
A	0010147	biological_process	fructan catabolic process
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0034484	biological_process	raffinose catabolic process
A	0051670	molecular_function	inulinase activity
A	0071944	cellular_component	cell periphery
A	1902927	biological_process	inulin catabolic process
B	0000324	cellular_component	fungal-type vacuole
B	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0004564	molecular_function	beta-fructofuranosidase activity
B	0004575	molecular_function	sucrose alpha-glucosidase activity
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005975	biological_process	carbohydrate metabolic process
B	0005987	biological_process	sucrose catabolic process
B	0010147	biological_process	fructan catabolic process
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0034484	biological_process	raffinose catabolic process
B	0051670	molecular_function	inulinase activity
B	0071944	cellular_component	cell periphery
B	1902927	biological_process	inulin catabolic process
C	0000324	cellular_component	fungal-type vacuole
C	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
C	0004564	molecular_function	beta-fructofuranosidase activity
C	0004575	molecular_function	sucrose alpha-glucosidase activity
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005975	biological_process	carbohydrate metabolic process
C	0005987	biological_process	sucrose catabolic process
C	0010147	biological_process	fructan catabolic process
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0034484	biological_process	raffinose catabolic process
C	0051670	molecular_function	inulinase activity
C	0071944	cellular_component	cell periphery
C	1902927	biological_process	inulin catabolic process
D	0000324	cellular_component	fungal-type vacuole
D	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
D	0004564	molecular_function	beta-fructofuranosidase activity
D	0004575	molecular_function	sucrose alpha-glucosidase activity
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005975	biological_process	carbohydrate metabolic process
D	0005987	biological_process	sucrose catabolic process
D	0010147	biological_process	fructan catabolic process
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0034484	biological_process	raffinose catabolic process
D	0051670	molecular_function	inulinase activity
D	0071944	cellular_component	cell periphery
D	1902927	biological_process	inulin catabolic process
E	0000324	cellular_component	fungal-type vacuole
E	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
E	0004564	molecular_function	beta-fructofuranosidase activity
E	0004575	molecular_function	sucrose alpha-glucosidase activity
E	0005576	cellular_component	extracellular region
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005975	biological_process	carbohydrate metabolic process
E	0005987	biological_process	sucrose catabolic process
E	0010147	biological_process	fructan catabolic process
E	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
E	0034484	biological_process	raffinose catabolic process
E	0051670	molecular_function	inulinase activity
E	0071944	cellular_component	cell periphery
E	1902927	biological_process	inulin catabolic process
F	0000324	cellular_component	fungal-type vacuole
F	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
F	0004564	molecular_function	beta-fructofuranosidase activity
F	0004575	molecular_function	sucrose alpha-glucosidase activity
F	0005576	cellular_component	extracellular region
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005975	biological_process	carbohydrate metabolic process
F	0005987	biological_process	sucrose catabolic process
F	0010147	biological_process	fructan catabolic process
F	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
F	0034484	biological_process	raffinose catabolic process
F	0051670	molecular_function	inulinase activity
F	0071944	cellular_component	cell periphery
F	1902927	biological_process	inulin catabolic process
G	0000324	cellular_component	fungal-type vacuole
G	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
G	0004564	molecular_function	beta-fructofuranosidase activity
G	0004575	molecular_function	sucrose alpha-glucosidase activity
G	0005576	cellular_component	extracellular region
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005975	biological_process	carbohydrate metabolic process
G	0005987	biological_process	sucrose catabolic process
G	0010147	biological_process	fructan catabolic process
G	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
G	0034484	biological_process	raffinose catabolic process
G	0051670	molecular_function	inulinase activity
G	0071944	cellular_component	cell periphery
G	1902927	biological_process	inulin catabolic process
H	0000324	cellular_component	fungal-type vacuole
H	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
H	0004564	molecular_function	beta-fructofuranosidase activity
H	0004575	molecular_function	sucrose alpha-glucosidase activity
H	0005576	cellular_component	extracellular region
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005975	biological_process	carbohydrate metabolic process
H	0005987	biological_process	sucrose catabolic process
H	0010147	biological_process	fructan catabolic process
H	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
H	0034484	biological_process	raffinose catabolic process
H	0051670	molecular_function	inulinase activity
H	0071944	cellular_component	cell periphery
H	1902927	biological_process	inulin catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00609
Number of Residues	14
Details	GLYCOSYL_HYDROL_F32 Glycosyl hydrolases family 32 active site. HftPnkgwMNDPNG

Chain	Residue	Details
A	HIS12-GLY25

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000255\|PROSITE-ProRule:PRU10067, ECO:0000269\|PubMed:2113524

Chain	Residue	Details
A	ASP22
B	ASP22
C	ASP22
D	ASP22
E	ASP22
F	ASP22
G	ASP22
H	ASP22

site_id	SWS_FT_FI2
Number of Residues	48
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	TRP19
B	ARG150
B	GLU203
B	TRP291
C	TRP19
C	GLN40
C	PHE82
C	ARG150
C	GLU203
C	TRP291
D	TRP19
A	GLN40
D	GLN40
D	PHE82
D	ARG150
D	GLU203
D	TRP291
E	TRP19
E	GLN40
E	PHE82
E	ARG150
E	GLU203
A	PHE82
E	TRP291
F	TRP19
F	GLN40
F	PHE82
F	ARG150
F	GLU203
F	TRP291
G	TRP19
G	GLN40
G	PHE82
A	ARG150
G	ARG150
G	GLU203
G	TRP291
H	TRP19
H	GLN40
H	PHE82
H	ARG150
H	GLU203
H	TRP291
A	GLU203
A	TRP291
B	TRP19
B	GLN40
B	PHE82

site_id	SWS_FT_FI3
Number of Residues	64
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:3284881

Chain	Residue	Details
A	ASN3
B	ASN77
B	ASN91
B	ASN98
B	ASN336
B	ASN349
B	ASN364
B	ASN378
C	ASN3
C	ASN77
C	ASN91
A	ASN77
C	ASN98
C	ASN336
C	ASN349
C	ASN364
C	ASN378
D	ASN3
D	ASN77
D	ASN91
D	ASN98
D	ASN336
A	ASN91
D	ASN349
D	ASN364
D	ASN378
E	ASN3
E	ASN77
E	ASN91
E	ASN98
E	ASN336
E	ASN349
E	ASN364
A	ASN98
E	ASN378
F	ASN3
F	ASN77
F	ASN91
F	ASN98
F	ASN336
F	ASN349
F	ASN364
F	ASN378
G	ASN3
A	ASN336
G	ASN77
G	ASN91
G	ASN98
G	ASN336
G	ASN349
G	ASN364
G	ASN378
H	ASN3
H	ASN77
H	ASN91
A	ASN349
H	ASN98
H	ASN336
H	ASN349
H	ASN364
H	ASN378
A	ASN364
A	ASN378
B	ASN3

site_id	SWS_FT_FI4
Number of Residues	40
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; partial => ECO:0000269\|PubMed:3284881

Chain	Residue	Details
A	ASN44
B	ASN492
C	ASN44
C	ASN145
C	ASN246
C	ASN255
C	ASN492
D	ASN44
D	ASN145
D	ASN246
D	ASN255
A	ASN145
D	ASN492
E	ASN44
E	ASN145
E	ASN246
E	ASN255
E	ASN492
F	ASN44
F	ASN145
F	ASN246
F	ASN255
A	ASN246
F	ASN492
G	ASN44
G	ASN145
G	ASN246
G	ASN255
G	ASN492
H	ASN44
H	ASN145
H	ASN246
H	ASN255
A	ASN255
H	ASN492
A	ASN492
B	ASN44
B	ASN145
B	ASN246
B	ASN255

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)