Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003756 | molecular_function | protein disulfide isomerase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0050451 | molecular_function | CoA-disulfide reductase (NADPH) activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0003756 | molecular_function | protein disulfide isomerase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0050451 | molecular_function | CoA-disulfide reductase (NADPH) activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG A 501 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 502 |
| Chain | Residue |
| A | ALA41 |
| A | CYS43 |
| A | COA505 |
| B | PHE361 |
| B | HOH3571 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 503 |
| Chain | Residue |
| A | HOH907 |
| A | HOH1241 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 504 |
| Chain | Residue |
| A | GLU87 |
| A | ARG88 |
| A | HOH1240 |
| A | ASN85 |
| site_id | AC5 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE COA A 505 |
| Chain | Residue |
| A | ALA14 |
| A | THR15 |
| A | SER18 |
| A | GLN19 |
| A | ARG22 |
| A | SER39 |
| A | PHE40 |
| A | ASN42 |
| A | CYS43 |
| A | TYR62 |
| A | LYS71 |
| A | ALA295 |
| A | HIS299 |
| A | CL502 |
| A | FAD506 |
| A | HOH729 |
| A | HOH764 |
| A | HOH849 |
| A | HOH954 |
| A | HOH983 |
| A | HOH1063 |
| A | HOH1085 |
| A | HOH1089 |
| A | HOH1096 |
| A | HOH1201 |
| A | HOH1213 |
| B | TYR419 |
| B | PRO426 |
| B | LYS427 |
| B | MET432 |
| B | TYR435 |
| B | MG3003 |
| site_id | AC6 |
| Number of Residues | 41 |
| Details | BINDING SITE FOR RESIDUE FAD A 506 |
| Chain | Residue |
| A | VAL7 |
| A | GLY8 |
| A | VAL10 |
| A | ALA11 |
| A | GLY12 |
| A | PHE32 |
| A | GLU33 |
| A | LYS34 |
| A | ASP35 |
| A | ASN42 |
| A | CYS43 |
| A | HIS79 |
| A | GLU80 |
| A | VAL81 |
| A | SER112 |
| A | PRO113 |
| A | GLY114 |
| A | LEU130 |
| A | ARG131 |
| A | TYR158 |
| A | VAL159 |
| A | PHE245 |
| A | GLY276 |
| A | ASP277 |
| A | PRO293 |
| A | LEU294 |
| A | ALA295 |
| A | ALA298 |
| A | COA505 |
| A | HOH601 |
| A | HOH602 |
| A | HOH604 |
| A | HOH610 |
| A | HOH612 |
| A | HOH613 |
| A | HOH630 |
| A | HOH640 |
| A | HOH651 |
| B | TYR419 |
| B | ALA420 |
| B | PRO421 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 3001 |
| Chain | Residue |
| A | PHE361 |
| A | HOH1239 |
| B | ALA41 |
| B | ASN42 |
| B | CYS43 |
| B | COA3006 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 3002 |
| Chain | Residue |
| A | HOH665 |
| A | HOH683 |
| A | HOH709 |
| A | HOH1240 |
| B | HOH3179 |
| B | HOH3214 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 3003 |
| Chain | Residue |
| B | HOH3286 |
| B | HOH3353 |
| A | COA505 |
| A | HOH781 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 3004 |
| Chain | Residue |
| B | VAL353 |
| B | THR354 |
| B | HOH3311 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 3005 |
| Chain | Residue |
| A | HOH709 |
| A | HOH1110 |
| B | ASN85 |
| B | ASP86 |
| B | GLU87 |
| B | ARG88 |
| site_id | BC3 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE COA B 3006 |
| Chain | Residue |
| A | MET432 |
| A | TYR435 |
| B | ALA11 |
| B | ALA14 |
| B | THR15 |
| B | SER18 |
| B | GLN19 |
| B | ARG22 |
| B | SER39 |
| B | PHE40 |
| B | ASN42 |
| B | CYS43 |
| B | ALA61 |
| B | TYR62 |
| B | LYS71 |
| B | ALA295 |
| B | HIS299 |
| B | CL3001 |
| B | FAD3007 |
| B | HOH3257 |
| B | HOH3418 |
| B | HOH3497 |
| B | HOH3501 |
| B | HOH3614 |
| site_id | BC4 |
| Number of Residues | 41 |
| Details | BINDING SITE FOR RESIDUE FAD B 3007 |
| Chain | Residue |
| A | TYR419 |
| A | ALA420 |
| A | PRO421 |
| B | VAL7 |
| B | GLY8 |
| B | VAL10 |
| B | ALA11 |
| B | GLY12 |
| B | PHE32 |
| B | GLU33 |
| B | LYS34 |
| B | ASP35 |
| B | ASN42 |
| B | CYS43 |
| B | HIS79 |
| B | GLU80 |
| B | VAL81 |
| B | SER112 |
| B | PRO113 |
| B | GLY114 |
| B | LEU130 |
| B | ARG131 |
| B | TYR158 |
| B | ASN242 |
| B | PHE245 |
| B | GLY276 |
| B | ASP277 |
| B | PRO293 |
| B | LEU294 |
| B | ALA295 |
| B | COA3006 |
| B | HOH3111 |
| B | HOH3114 |
| B | HOH3115 |
| B | HOH3127 |
| B | HOH3129 |
| B | HOH3135 |
| B | HOH3138 |
| B | HOH3149 |
| B | HOH3156 |
| B | HOH3419 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Redox-active","evidences":[{"source":"HAMAP-Rule","id":"MF_01608","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 118 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01608","evidenceCode":"ECO:0000255"}]} |
