Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003756 | molecular_function | protein disulfide isomerase activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0050451 | molecular_function | CoA-disulfide reductase (NADPH) activity |
A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
A | 0050661 | molecular_function | NADP binding |
B | 0003756 | molecular_function | protein disulfide isomerase activity |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0050451 | molecular_function | CoA-disulfide reductase (NADPH) activity |
B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG A 501 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL A 502 |
Chain | Residue |
A | ALA41 |
A | CYS43 |
A | COA505 |
B | PHE361 |
B | HOH3571 |
site_id | AC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL A 503 |
Chain | Residue |
A | HOH907 |
A | HOH1241 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 504 |
Chain | Residue |
A | GLU87 |
A | ARG88 |
A | HOH1240 |
A | ASN85 |
site_id | AC5 |
Number of Residues | 32 |
Details | BINDING SITE FOR RESIDUE COA A 505 |
Chain | Residue |
A | ALA14 |
A | THR15 |
A | SER18 |
A | GLN19 |
A | ARG22 |
A | SER39 |
A | PHE40 |
A | ASN42 |
A | CYS43 |
A | TYR62 |
A | LYS71 |
A | ALA295 |
A | HIS299 |
A | CL502 |
A | FAD506 |
A | HOH729 |
A | HOH764 |
A | HOH849 |
A | HOH954 |
A | HOH983 |
A | HOH1063 |
A | HOH1085 |
A | HOH1089 |
A | HOH1096 |
A | HOH1201 |
A | HOH1213 |
B | TYR419 |
B | PRO426 |
B | LYS427 |
B | MET432 |
B | TYR435 |
B | MG3003 |
site_id | AC6 |
Number of Residues | 41 |
Details | BINDING SITE FOR RESIDUE FAD A 506 |
Chain | Residue |
A | VAL7 |
A | GLY8 |
A | VAL10 |
A | ALA11 |
A | GLY12 |
A | PHE32 |
A | GLU33 |
A | LYS34 |
A | ASP35 |
A | ASN42 |
A | CYS43 |
A | HIS79 |
A | GLU80 |
A | VAL81 |
A | SER112 |
A | PRO113 |
A | GLY114 |
A | LEU130 |
A | ARG131 |
A | TYR158 |
A | VAL159 |
A | PHE245 |
A | GLY276 |
A | ASP277 |
A | PRO293 |
A | LEU294 |
A | ALA295 |
A | ALA298 |
A | COA505 |
A | HOH601 |
A | HOH602 |
A | HOH604 |
A | HOH610 |
A | HOH612 |
A | HOH613 |
A | HOH630 |
A | HOH640 |
A | HOH651 |
B | TYR419 |
B | ALA420 |
B | PRO421 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CL B 3001 |
Chain | Residue |
A | PHE361 |
A | HOH1239 |
B | ALA41 |
B | ASN42 |
B | CYS43 |
B | COA3006 |
site_id | AC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG B 3002 |
Chain | Residue |
A | HOH665 |
A | HOH683 |
A | HOH709 |
A | HOH1240 |
B | HOH3179 |
B | HOH3214 |
site_id | AC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG B 3003 |
Chain | Residue |
B | HOH3286 |
B | HOH3353 |
A | COA505 |
A | HOH781 |
site_id | BC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 3004 |
Chain | Residue |
B | VAL353 |
B | THR354 |
B | HOH3311 |
site_id | BC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CL B 3005 |
Chain | Residue |
A | HOH709 |
A | HOH1110 |
B | ASN85 |
B | ASP86 |
B | GLU87 |
B | ARG88 |
site_id | BC3 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE COA B 3006 |
Chain | Residue |
A | MET432 |
A | TYR435 |
B | ALA11 |
B | ALA14 |
B | THR15 |
B | SER18 |
B | GLN19 |
B | ARG22 |
B | SER39 |
B | PHE40 |
B | ASN42 |
B | CYS43 |
B | ALA61 |
B | TYR62 |
B | LYS71 |
B | ALA295 |
B | HIS299 |
B | CL3001 |
B | FAD3007 |
B | HOH3257 |
B | HOH3418 |
B | HOH3497 |
B | HOH3501 |
B | HOH3614 |
site_id | BC4 |
Number of Residues | 41 |
Details | BINDING SITE FOR RESIDUE FAD B 3007 |
Chain | Residue |
A | TYR419 |
A | ALA420 |
A | PRO421 |
B | VAL7 |
B | GLY8 |
B | VAL10 |
B | ALA11 |
B | GLY12 |
B | PHE32 |
B | GLU33 |
B | LYS34 |
B | ASP35 |
B | ASN42 |
B | CYS43 |
B | HIS79 |
B | GLU80 |
B | VAL81 |
B | SER112 |
B | PRO113 |
B | GLY114 |
B | LEU130 |
B | ARG131 |
B | TYR158 |
B | ASN242 |
B | PHE245 |
B | GLY276 |
B | ASP277 |
B | PRO293 |
B | LEU294 |
B | ALA295 |
B | COA3006 |
B | HOH3111 |
B | HOH3114 |
B | HOH3115 |
B | HOH3127 |
B | HOH3129 |
B | HOH3135 |
B | HOH3138 |
B | HOH3149 |
B | HOH3156 |
B | HOH3419 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | CYS43 | |
B | CYS43 | |
Chain | Residue | Details |
A | GLY8 | |
A | HIS299 | |
A | TYR419 | |
A | LYS427 | |
B | GLY8 | |
B | THR15 | |
B | GLN19 | |
B | ARG22 | |
B | SER39 | |
B | ASN42 | |
B | LYS71 | |
A | THR15 | |
B | VAL151 | |
B | THR267 | |
B | HIS299 | |
B | TYR419 | |
B | LYS427 | |
A | GLN19 | |
A | ARG22 | |
A | SER39 | |
A | ASN42 | |
A | LYS71 | |
A | VAL151 | |
A | THR267 | |