4EP4
Thermus thermophilus RuvC structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004520 | molecular_function | DNA endonuclease activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006281 | biological_process | DNA repair |
| A | 0006310 | biological_process | DNA recombination |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048476 | cellular_component | Holliday junction resolvase complex |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0004520 | molecular_function | DNA endonuclease activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006281 | biological_process | DNA repair |
| B | 0006310 | biological_process | DNA recombination |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048476 | cellular_component | Holliday junction resolvase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 201 |
| Chain | Residue |
| B | ASP7 |
| B | HIS143 |
| B | HOH328 |
| B | HOH448 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 202 |
| Chain | Residue |
| B | HOH307 |
| B | HOH319 |
| B | HOH402 |
| B | HOH439 |
| A | GLU123 |
| A | HOH341 |
| B | MET1 |
| B | GLU65 |
| B | ALA158 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Motif: {"description":"Wedge","evidences":[{"source":"PubMed","id":"31506434","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00034","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23118486","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"23980027","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"31506434","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"23118486","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00034","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23118486","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EP4","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23980027","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31506434","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4LD0","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"6S16","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00034","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23980027","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31506434","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23118486","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4LD0","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23980027","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31506434","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4LD0","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31506434","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23980027","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6S16","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23980027","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4LD0","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
