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4EO7

Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88.

Functional Information from GO Data
ChainGOidnamespacecontents
A0002755biological_processMyD88-dependent toll-like receptor signaling pathway
A0007165biological_processsignal transduction
A0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
A0070976molecular_functionTIR domain binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG A 301
ChainResidue
ALYS238
APRO279
ALYS282
AHOH451

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER244

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PDB entries from 2024-06-12

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