4EMV

Crystal structure of a topoisomerase ATP inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE 0R9 A 301

Chain	Residue
A	ASN51
A	ILE98
A	HIS120
A	VAL122
A	ARG140
A	THR172
A	HOH430
A	HOH466
A	HOH505
A	HOH531
A	HOH532
A	GLU55
A	VAL76
A	ASP78
A	ARG81
A	GLY82
A	MET83
A	PRO84
A	THR94

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